GNAI2 cdna clone
GNAI2 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins). The encoded protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Uniprot Description
G-alpha i2: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division. Belongs to the G-alpha family. G(i/o/t/z) subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: G protein, heterotrimeric; G protein; G protein, heterotrimeric alpha G((i/o/t/z))
Chromosomal Location of Human Ortholog: 3p21.31
Cellular Component: centrosome; cytoplasm; heterotrimeric G-protein complex; membrane; midbody; nucleoplasm; plasma membrane
Molecular Function: G-protein beta/gamma-subunit binding; G-protein-coupled receptor binding; GTP binding; GTPase activity; protein binding; signal transducer activity
Biological Process: adenosine receptor signaling pathway; cell division; G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; gamma-aminobutyric acid signaling pathway; negative regulation of adenylate cyclase activity; protein folding; response to nutrient; signal transduction
Disease: Ventricular Tachycardia, Familial
Research Articles on GNAI2
Similar Products
Product Notes
The GNAI2 gnai2 (Catalog #AAA1265777) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgggctgca ccgtgagcgc cgaggacaag gcggcggccg agcgctctaa gatgatcgac aagaacctgc gggaggacgg agagaaggcg gcgcgggagg tgaagttgct gctgttgggt gctggggagt cagggaagag caccatcgtc aagcagatga agatcatcca cgaggatggc tactccgagg aggaatgccg gcagtaccgg gcggttgtct acagcaacac catccagtcc atcatggcca ttgtcaaagc catgggcaac ctgcagatcg actttgccga cccctccaga gcggacgacg ccaggcagct atttgcactg tcctgcaccg ccgaggagca aggcgtgctc cctgatgacc tgtccggcgt catccggagg ctctgggctg accatggtgt gcaggcctgc tttggccgct caagggaata ccagctcaac gactcagctg cctactacct gaacgacctg gagcgtattg cacagagtga ctacatcccc acacagcaag atgtgctacg gacccgcgta aagaccacgg ggatcgtgga gacacacttc accttcaagg acctacactt caagatgttt gatgtgggtg gtcagcggtc tgagcggaag aagtggatcc actgctttga gggcgtcaca gccatcatct tctgcgtagc cttgagcgcc tatgacttgg tgctagctga ggacgaggag atgaaccgca tgcatgagag catgaagcta ttcgatagca tctgcaacaa caagtggttc acagacacgt ccatcatcct cttcctcaac aagaaggacc tgtttgagga gaagatcaca cacagtcccc tgaccatctg cttccctgag tacacagggg ccaacaaata tgatgaggca gccagctaca tccagagtaa gtttgaggac ctgaataagc gcaaagacac caaggagatc tacacgcact tcacgtgcgc caccgacacc aagaacgtgc agttcgtgtt tgacgccgtc accgatgtca tcatcaagaa caacctgaag gactgcggcc tcttctga. It is sometimes possible for the material contained within the vial of "GNAI2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
