Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded rat kidney tissue slide using MBS769764 (GNAI2 Antibody) at dilution of 1:50)
Rabbit GNAI2 Polyclonal Antibody | anti-GNAI2 antibody
GNAI2 Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded rat kidney tissue slide using MBS769764 (GNAI2 Antibody) at dilution of 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded rat kidney tissue slide using MBS769764 (GNAI2 Antibody) at dilution of 1:50)
Immunofluorescence (IF)
(Immunofluorescent analysis of Hela cells, using MBS769764 (GNAI2 Antibody) at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG.)
Immunofluorescence (IF)
(Immunofluorescent analysis of Hela cells, using MBS769764 (GNAI2 Antibody) at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG.)
Immunoprecipitation (IP)
(IP Result of anti-GNAI2 (IP: MBS769764, 4ug; Detection: MBS769764 1:1000) with mouse kidney tissue lysate 3000ug.)
Immunoprecipitation (IP)
(IP Result of anti-GNAI2 (IP: MBS769764, 4ug; Detection: MBS769764 1:1000) with mouse kidney tissue lysate 3000ug.)
Western Blot (WB)
(Jurkat cells were subjected to SDS PAGE followed by western blot with MBS769764 (GNAI2 antibody) at dilution of 1:1000)
Western Blot (WB)
(Jurkat cells were subjected to SDS PAGE followed by western blot with MBS769764 (GNAI2 antibody) at dilution of 1:1000)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins). The encoded protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Uniprot Description
G-alpha i2: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division. Belongs to the G-alpha family. G(i/o/t/z) subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: G protein, heterotrimeric alpha G((i/o/t/z)); G protein; G protein, heterotrimeric
Chromosomal Location of Human Ortholog: 3p21.31
Cellular Component: centrosome; cytoplasm; cytosol; dendrite; heterotrimeric G-protein complex; lipid raft; membrane; midbody; nucleoplasm; plasma membrane
Molecular Function: G-protein beta/gamma-subunit binding; G-protein-coupled receptor binding; GTP binding; GTPase activity; metal ion binding; protein binding; signal transducer activity
Biological Process: acetylcholine receptor signaling, muscarinic pathway; activation of MAPKK activity; adenosine receptor signaling pathway; cell cycle; cell division; cell proliferation; G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; gamma-aminobutyric acid signaling pathway; metabolic process; negative regulation of adenylate cyclase activity; negative regulation of synaptic transmission; positive regulation of cell proliferation; protein folding; regulation of calcium ion transport; response to nutrient; signal transduction
Disease: Ventricular Tachycardia, Familial
Research Articles on GNAI2
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Product Notes
The GNAI2 gnai2 (Catalog #AAA769764) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GNAI2 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GNAI2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP). WB (1:500-1:2000);IP (1:500-1:2000); IHC (1:50-1:500); IF(1:10-1:100). Researchers should empirically determine the suitability of the GNAI2 gnai2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GNAI2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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