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Major surface glycoprotein G (G) Recombinant Protein | G recombinant protein

Recombinant Human respiratory syncytial virus A Major surface glycoprotein G (G)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Major surface glycoprotein G (G); Recombinant Human respiratory syncytial virus A Major surface glycoprotein G (G); Recombinant Major surface glycoprotein G (G); Major surface glycoprotein G; Attachment glycoprotein G Membrane-bound glycoprotein; mG; G recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-297
Sequence
MSKNKDQRTAKTLERTWDTLNHLLFISSCLYKLNLKSVAQITLSILAMIISTSLIIAAIIFIASANHRVTSTTTIIQDATNQIKNTTPTYLTQNPQLGISPSNPSEITSLITTILDPTTPGVKLTLQSTTVRIKNTTTTQAQPNKSTTKQRQNKPPSKPNNDFHFEVFNFVPCSICSNNPTCWAICKRIPNKKPGKRTTTKPTKKPTLKTTKKDPKPQTTKSEEVPTTKLTEEPTINTTKTNIITTPLTSNTARNPELTSQMETFHSTSSEGNPSPSQVSITSEYPPQPSSPPNTPR
Sequence Length
297
Species
Human respiratory syncytial virus A (strain rsb642)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
32,745 Da
NCBI Official Full Name
Major surface glycoprotein G
UniProt Protein Name
Major surface glycoprotein G
UniProt Gene Name
G
UniProt Synonym Gene Names
mG
UniProt Entry Name
GLYC_HRSV2

Uniprot Description

Function: Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities

By similarity.Secreted glycoprotein G helps RSV escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fcgamma receptors

By similarity.

Subunit structure: Homooligomer. Interacts (via N-terminus) with protein M. Interacts with protein F; this interaction occurs on the surface of infected cells. Interacts with protein SH. Interacts with host CX3CR1; this interaction modulates host immune response

By similarity.

Subcellular location: Virion membrane. Host cell surface

By similarity. Isoform Secreted glycoprotein G: Secreted.

Domain: Contains a linear heparin binding domain essential for virus attachment to the host

By similarity.

Post-translational modification: May carry a lot of separate O-linked carbohydrate chains distributed among serine and threonine residues

By similarity.Palmitoylated

By similarity.

Sequence similarities: Belongs to the pneumoviruses glycoprotein G family.

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Product Notes

The Major surface glycoprotein G (G) g (Catalog #AAA1250499) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-297. The amino acid sequence is listed below: MSKNKDQRTA KTLERTWDTL NHLLFISSCL YKLNLKSVAQ ITLSILAMII STSLIIAAII FIASANHRVT STTTIIQDAT NQIKNTTPTY LTQNPQLGIS PSNPSEITSL ITTILDPTTP GVKLTLQSTT VRIKNTTTTQ AQPNKSTTKQ RQNKPPSKPN NDFHFEVFNF VPCSICSNNP TCWAICKRIP NKKPGKRTTT KPTKKPTLKT TKKDPKPQTT KSEEVPTTKL TEEPTINTTK TNIITTPLTS NTARNPELTS QMETFHSTSS EGNPSPSQVS ITSEYPPQPS SPPNTPR. It is sometimes possible for the material contained within the vial of "Major surface glycoprotein G (G), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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