Histone H3-like centromeric protein hcp-3 (hcp-3) Recombinant Protein | hcp-3 recombinant protein
Recombinant Caenorhabditis elegans Histone H3-like centromeric protein hcp-3 (hcp-3)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Histone H3-like centromeric protein hcp-3 (hcp-3); Recombinant Caenorhabditis elegans Histone H3-like centromeric protein hcp-3 (hcp-3); hcp-3 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-288, Full length
Sequence
MADDTPIIEEIAEQNESVTRIMQRLKHDMQRVTSVPGFNTSAAGVNDLIDILNQYKKELEDDAANDYTEAHIHKIRLVTGKRNQYVLKLKQAEDEYHARKEQARRRASSMDFTVGRNSTNLVDYSHGRHHMPSYRRHDSSDEENYSMDGTNGDGNRAGPSNPDRGNRTGPSSSDRVRMRAGRNRVTKTRRYRPGQKALEEIRKYQKTEDLLIQKAPFARLVREIMQTSTPFGADCRIRSDAISALQEAAEAFLVEMFEGSSLISTHAKRVTLMTTDIQLYRRLCLRHL
Sequence Length
288
Species
Caenorhabditis elegans
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
32,997 Da
NCBI Official Full Name
Histone H3-like centromeric protein hcp-3
NCBI Official Symbol
hcp-3
NCBI Protein Information
Histone H3-like centromeric protein hcp-3
UniProt Protein Name
Histone H3-like centromeric protein hcp-3
Protein Family
UniProt Gene Name
hcp-3
Uniprot Description
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore (PubMed:10524621). Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation (PubMed:11402065, PubMed:14522947, PubMed:16273096, PubMed:16950114, PubMed:16950115). May serve as an epigenetic mark that propagates centromere identity through replication and cell division (). Might promote cleavage furrow stability during cytokinesis (PubMed:23684975). Not required for chromosome segregation during meiosis (PubMed:16273096).
Research Articles on hcp-3
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Product Notes
The hcp-3 hcp-3 (Catalog #AAA1237229) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-288, Full length. The amino acid sequence is listed below: MADDTPIIEE IAEQNESVTR IMQRLKHDMQ RVTSVPGFNT SAAGVNDLID ILNQYKKELE DDAANDYTEA HIHKIRLVTG KRNQYVLKLK QAEDEYHARK EQARRRASSM DFTVGRNSTN LVDYSHGRHH MPSYRRHDSS DEENYSMDGT NGDGNRAGPS NPDRGNRTGP SSSDRVRMRA GRNRVTKTRR YRPGQKALEE IRKYQKTEDL LIQKAPFARL VREIMQTSTP FGADCRIRSD AISALQEAAE AFLVEMFEGS SLISTHAKRV TLMTTDIQLY RRLCLRHL. It is sometimes possible for the material contained within the vial of "Histone H3-like centromeric protein hcp-3 (hcp-3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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