Transcription factor AS1 (AS1) Recombinant Protein | AS1 recombinant protein

Recombinant Arabidopsis thaliana Transcription factor AS1 (AS1)

Cat. Num. AAA1141262

• Gene Names: AS1; ARABIDOPSIS PHANTASTICA-LIKE 1; ASYMMETRIC LEAVES 1; ATMYB91; ATPHAN; F13M22.13; F13M22_13; MYB DOMAIN PROTEIN 91; MYB91
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Transcription factor AS1 (AS1); Recombinant Arabidopsis thaliana Transcription factor AS1 (AS1); AS1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-367, Full length protein
• Sequence: MKERQRWSGEEDALLRAYVRQFGPREWHLVSERMNKPLNRDAKSCLERWKNYLKPGIKKGSLTEEEQRLVIRLQEKHGNKWKKIAAEVPGRTAKRLGKWWEVFKEKQQREEKESNKRVEPIDESKYDRILESFAEKLVKERSNVVPAAAAAATVVMANSNGGFLHSEQQVQPPNPVIPPWLATSNNGNNVVARPPSVTLTLSPSTVAAAAPQPPIPWLQQQQPERAENGPGGLVLGSMMPSCSGSSESVFLSELVECCRELEEGHRAWADHKKEAAWRLRRLELQLESEKTCRQREKMEEIEAKMKALREEQKNAMEKIEGEYREQLVGLRRDAEAKDQKLADQWTSRHIRLTKFLEQQMGCRLDRP
• Sequence Length: 367

• Species: Arabidopsis thaliana (Mouse-ear cress)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 15224328
• NCBI GeneID: 818340
• NCBI Accession #: NP_181299.1
• NCBI GenBank Nucleotide #: NM_129319.4
• UniProt Accession #: O80931; Q53YQ1
• Molecular Weight: 42,243 Da
• NCBI Official Full Name: myb-like HTH transcriptional regulator family protein
• NCBI Official Symbol: AS1
• NCBI Official Synonym Symbols: ARABIDOPSIS PHANTASTICA-LIKE 1; ASYMMETRIC LEAVES 1; ATMYB91; ATPHAN; F13M22.13; F13M22_13; MYB DOMAIN PROTEIN 91; MYB91
• NCBI Protein Information: myb-like HTH transcriptional regulator family protein
• UniProt Protein Name: Transcription factor AS1
• Protein Family: Transcription factor
• UniProt Gene Name: AS1
• UniProt Synonym Gene Names: AtPHAN

NCBI Description

Encodes a MYB-domain protein involved in specification of the leaf proximodistal axis. Mutation results in lobed and dissected leaves with a characteristic asymmetry. Homologous to the Antirrhinum PHANTASTICA (PHAN) and maize ROUGH SHEATH2 (RS2) genes Asymmetric placement of auxin response at the distal leaf tip precedes visible asymmetric leaf growth. Acts alongside AXR1 to exclude BP expression in leaves and with PIN1 to repress BP and promote lateral organ growth. Interacts physically with AS2 to form a complex that binds to the BP promoter and silences BP. Also functions as a regulator of the plant immune response.

Uniprot Description

Transcription factor required for normal cell differentiation. Positively regulates LATERAL ORGAN BOUNDARIES (LOB) within the shoot apex, and the class III HD-ZIP genes REV, PHB, and PHV. Interacts directly with ASYMMETRIC LEAVES 2 (LBD6/AS2) to repress the knox homeobox genes BP/KNAT1, KNAT2, and KNAT6 and the abaxial determinants ARF3/ETT, KAN2 and YAB5. May act in parallel with the RDR6-SGS3-AGO7 pathway, an endogenous RNA silencing pathway, to regulate the leaf morphogenesis (PubMed:11076771, PubMed:11140682, PubMed:11882937, PubMed:12750468, PubMed:16006579, PubMed:16699177, PubMed:17395603, PubMed:17559509, PubMed:23271976). Binds directly to KNAT1, KNAT2, and KNATM chromatin, regulating leaf development (PubMed:23271976). LBD6 is required for this binding (PubMed:23271976). Positive regulator of flowering that binds to the promoter of FT (PubMed:21950734). Regulates FT expression by forming a functional complex with CO (PubMed:21950734).