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Solute carrier organic anion transporter family member 1A3 (Slco1a3) Recombinant Protein | Slco1a3 recombinant protein

Recombinant Rat Solute carrier organic anion transporter family member 1A3 (Slco1a3), partial

Gene Names
Slc21a4; OAT-K1; OAT-K2; Slco1a3; rOAT-K1; rOAT-K2; rOAT-K3; rOAT-K5; rOAT-K6; rOAT-K7; rOAT-K8; rOAT-K9; rOAT-K11; rOAT-K13; rOAT-K14
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Solute carrier organic anion transporter family member 1A3 (Slco1a3); Recombinant Rat Solute carrier organic anion transporter family member 1A3 (Slco1a3); partial; Slco1a3 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-670
Sequence
MGDLEKGAATHGAGCFAKIKVFLMALTCAYVSKSLSGTFMSSMLTQIERQFGIPTAIVGFINGSFEIGNLLLIIFVSYFGMKLHRPIVIGVGCAVMGLGCFIISLPHFLMGRYEYETTILPTSNLSSNSFLCMENQTQTLNPAQDPAECVKEVKSLMWIYVLVGNIIRGIGETPIMPLGVSYIENFAKSENSPLYIGILETGKMIGPIFGLLLGSFCASIYVDTGSVNTDDLTITPTDIRWVGAWWIGFLVCAGVNILISIPFFFFPKTLPKEGLQENVDGTENAKEESTEKRPRKKNRGITKDFFPFLKSPVLQPDLHAVHPYKVLQVNAFNIYFSFLPKYLENQYGKSTAEVIFLMGVYNLPAICIGYLIAGFMMKKFKITVKTAAFLAFCLSLSEYSFGFCNFLITCDNVPVAGLTNSYERDQKPLYLENNVLADCNTRCSCLTKTWDPVCGDNGLAYMSACLAGCEKSVGTGTNMVFHNCSCIQSPGNSSAVLGLCNKGPECTNKLQYLLILSGFLSILYSFAAIPGYMVFLRCIKSEEKSLGIGIHAFCIRVFAGIPAPIYFGALIDRTCLHWGTQKCGAPGACRMYDINSFRRIYLGMSAALRGSSYLPAFVIVILTRKFSLPGKINSSEMEIAEMKLTEKESQCTDVHRNPKFKNDGELKTKL
Sequence Length
670
Species
Rattus norvegicus (Rat)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
61,049 Da
NCBI Official Full Name
solute carrier organic anion transporter family member 1A3
NCBI Official Synonym Full Names
kidney specific organic anion transporter
NCBI Official Symbol
Slc21a4
NCBI Official Synonym Symbols
OAT-K1; OAT-K2; Slco1a3; rOAT-K1; rOAT-K2; rOAT-K3; rOAT-K5; rOAT-K6; rOAT-K7; rOAT-K8; rOAT-K9; rOAT-K11; rOAT-K13; rOAT-K14
NCBI Protein Information
solute carrier organic anion transporter family member 1A3
UniProt Protein Name
Solute carrier organic anion transporter family member 1A3
UniProt Gene Name
Slco1a3
UniProt Synonym Gene Names
Oatp1a3; Slc21a4; OAT-K1

NCBI Description

plays a role in methotrexate transport; may facilitate basolateral membrane uptake and renal clearance of methotrexate from the blood [RGD, Feb 2006]

Uniprot Description

Mediates the Na+-independent transport of organic anions such as methotrexate, taurocholate, folate and prostaglandin E2. May contribute to renal secretion and/or reabsorption of hydrophobic anionic compounds. Mediates renal clearance of methotrexate from the blood.

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Product Notes

The Slco1a3 slco1a3 (Catalog #AAA1105355) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-670. The amino acid sequence is listed below: MGDLEKGAAT HGAGCFAKIK VFLMALTCAY VSKSLSGTFM SSMLTQIERQ FGIPTAIVGF INGSFEIGNL LLIIFVSYFG MKLHRPIVIG VGCAVMGLGC FIISLPHFLM GRYEYETTIL PTSNLSSNSF LCMENQTQTL NPAQDPAECV KEVKSLMWIY VLVGNIIRGI GETPIMPLGV SYIENFAKSE NSPLYIGILE TGKMIGPIFG LLLGSFCASI YVDTGSVNTD DLTITPTDIR WVGAWWIGFL VCAGVNILIS IPFFFFPKTL PKEGLQENVD GTENAKEEST EKRPRKKNRG ITKDFFPFLK SPVLQPDLHA VHPYKVLQVN AFNIYFSFLP KYLENQYGKS TAEVIFLMGV YNLPAICIGY LIAGFMMKKF KITVKTAAFL AFCLSLSEYS FGFCNFLITC DNVPVAGLTN SYERDQKPLY LENNVLADCN TRCSCLTKTW DPVCGDNGLA YMSACLAGCE KSVGTGTNMV FHNCSCIQSP GNSSAVLGLC NKGPECTNKL QYLLILSGFL SILYSFAAIP GYMVFLRCIK SEEKSLGIGI HAFCIRVFAG IPAPIYFGAL IDRTCLHWGT QKCGAPGACR MYDINSFRRI YLGMSAALRG SSYLPAFVIV ILTRKFSLPG KINSSEMEIA EMKLTEKESQ CTDVHRNPKF KNDGELKTKL. It is sometimes possible for the material contained within the vial of "Solute carrier organic anion transporter family member 1A3 (Slco1a3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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