Human zinc finger, RAN-binding domain containing 1 ELISA Kit | ZRANB1 elisa kit
Human Ubiquitin thioesterase ZRANB1, ZRANB1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
ZRANB1: Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'- linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling. Belongs to the peptidase C64 family.
Protein type: EC 3.4.19.12; Protease; Ubiquitin conjugating system; Ligase; Ubiquitin-specific protease
Chromosomal Location of Human Ortholog: 10q26.13
Cellular Component: nucleoplasm; cytoplasm; nucleus
Molecular Function: protein binding; zinc ion binding; ubiquitin-specific protease activity
Biological Process: cell migration; Wnt receptor signaling pathway; regulation of cell morphogenesis; cytoskeleton organization and biogenesis; positive regulation of Wnt receptor signaling pathway
Research Articles on ZRANB1
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Product Notes
The Human ZRANB1 zranb1 (Catalog #AAA9327673) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9327673 ELISA Kit recognizes Human ZRANB1. It is sometimes possible for the material contained within the vial of "zinc finger, RAN-binding domain containing 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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