P-glycoprotein Recombinant Antibody | ABCB1 recombinant antibody
Anti-P-glycoprotein [MRK16]
Gene Names
ABCB1; CLCS; MDR1; P-GP; PGY1; ABC20; CD243; GP170
Reactivity
Human
Applications
Immunoprecipitation, Immunofluorescence, Flow Cytometry, Functional Assay
Purity
Protein A Affinity Purified
Synonyms
P-glycoprotein; N/A; Anti-P-glycoprotein [MRK16]; ABCB1; Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; CD243; MDR1; PGP; PGY1; ABCB1 recombinant antibody
Reactivity
Human
Isotype
Mouse IgG1, kappa
Clone Number
MRK16
Specificity
Recognizes a discontinuous extracellular epitope on P-glycoprotein.
Purity/Purification
Protein A Affinity Purified
Form/Format
PBS only with 0.02% Proclin 300.
Concentration
1mg/ml (varies by lot)
Sequence Length
1280
Applicable Applications for ABCB1 recombinant antibody
IP (Immunoprecipitation), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
Immunogen
Drug resistant K-562 cells.
Preparation and Storage
Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
Related Product Information for ABCB1 recombinant antibody
Note on Publication: Describes the generation of the antibody and its ability to modulate drug cytotoxicity in vitro.
Product Categories/Family for ABCB1 recombinant antibody
References
Hamada H, Tsuruo T. Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies. Proc Natl Acad Sci U S A. 1986 Oct; 83(20):7785-9. PMID: 2429319
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Multidrug resistance protein 1
NCBI Official Synonym Full Names
ATP binding cassette subfamily B member 1
NCBI Official Symbol
ABCB1
NCBI Official Synonym Symbols
CLCS; MDR1; P-GP; PGY1; ABC20; CD243; GP170
NCBI Protein Information
multidrug resistance protein 1
UniProt Protein Name
Multidrug resistance protein 1
UniProt Gene Name
ABCB1
UniProt Synonym Gene Names
MDR1; PGY1
UniProt Entry Name
MDR1_HUMAN
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Product Notes
The ABCB1 abcb1 (Catalog #AAA71936) is a Recombinant Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-P-glycoprotein [MRK16] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's P-glycoprotein can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IF (Immunofluorescence), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the ABCB1 abcb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "P-glycoprotein, Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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