Human zinc finger protein 274 ELISA Kit | ZNF274 elisa kit
Human Neurotrophin receptor-interacting factor homolog, ZNF274 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals. [provided by RefSeq, Jul 2008]
Uniprot Description
ZNF274: Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin- modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression. Belongs to the krueppel C2H2-type zinc-finger protein family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding; C2H2-type zinc finger protein; Transcription factor; Nucleolus
Chromosomal Location of Human Ortholog: 19qter
Cellular Component: nucleoplasm; centrosome; cytoplasm; nucleolus; nucleus
Molecular Function: protein binding; sequence-specific DNA binding; metal ion binding; transcription corepressor activity; transcription factor activity
Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
Research Articles on ZNF274
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Product Notes
The Human ZNF274 znf274 (Catalog #AAA9325148) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9325148 ELISA Kit recognizes Human ZNF274. It is sometimes possible for the material contained within the vial of "zinc finger protein 274, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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