Zygotic DNA replication licensing factor mcm3 (zmcm3) Recombinant Protein | zmcm3 recombinant protein

Recombinant Xenopus laevis Zygotic DNA replication licensing factor mcm3 (zmcm3), partial

• Gene Names: zmcm3.L; mcm3
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Zygotic DNA replication licensing factor mcm3 (zmcm3); Recombinant Xenopus laevis Zygotic DNA replication licensing factor mcm3 (zmcm3); partial; zmcm3 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 806

• Species: Xenopus laevis (African clawed frog)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 148235010
• NCBI GeneID: 379850
• NCBI Accession #: NP_001080158.1
• NCBI GenBank Nucleotide #: NM_001086689.1
• UniProt Accession #: Q7ZXZ0
• Molecular Weight: 90,547 Da
• NCBI Official Full Name: zygotic DNA replication licensing factor mcm3
• NCBI Official Synonym Full Names: Putative ortholog of dNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF beta subunit) (P102 protein) (P1-MCM3), 1 of 1 L homeolog
• NCBI Official Symbol: zmcm3.L
• NCBI Official Synonym Symbols: mcm3
• NCBI Protein Information: zygotic DNA replication licensing factor mcm3
• UniProt Protein Name: Zygotic DNA replication licensing factor mcm3
• Protein Family: Zygotic DNA replication licensing factor
• UniProt Gene Name: zmcm3
• UniProt Synonym Gene Names: zMCM3

Uniprot Description

Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. The existence of maternal and zygotic forms of mcm3 and mcm6 suggests that specific forms of mcm2-7 complexes may be used during different stages of development.