Human zinc finger CCCH-type containing 8 ELISA Kit | ZC3H8 elisa kit
Human Zinc finger CCCH domain-containing protein 8, ZC3H8 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
ZC3H8: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 2q13
Cellular Component: Cajal body; transcription elongation factor complex; nucleus
Molecular Function: protein binding; sequence-specific DNA binding; metal ion binding; transcription factor activity
Biological Process: response to antibiotic; apoptosis; positive regulation of transcription from RNA polymerase III promoter; snRNA transcription from RNA polymerase II promoter; T cell homeostasis; negative regulation of T cell differentiation in the thymus; negative regulation of transcription, DNA-dependent; snRNA transcription from RNA polymerase III promoter
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Product Notes
The Human ZC3H8 zc3h8 (Catalog #AAA9339609) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9339609 ELISA Kit recognizes Human ZC3H8. It is sometimes possible for the material contained within the vial of "zinc finger CCCH-type containing 8, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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