Western Blot (WB)
(K-562 cells were subjected to SDS PAGE followed by western blot with MBS7605838 (ZC3H8 Antibody) at dilution of 1:2000)
Rabbit anti-Human ZC3H8 Polyclonal Antibody | anti-ZC3H8 antibody
ZC3H8 Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Western Blot (WB)
(K-562 cells were subjected to SDS PAGE followed by western blot with MBS7605838 (ZC3H8 Antibody) at dilution of 1:2000)
Western Blot (WB)
(K-562 cells were subjected to SDS PAGE followed by western blot with MBS7605838 (ZC3H8 Antibody) at dilution of 1:2000)
NCBI and Uniprot Product Information
Uniprot Description
ZC3H8: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 2q13
Cellular Component: Cajal body; nucleoplasm; nucleus; transcription elongation factor complex
Molecular Function: metal ion binding; protein binding; sequence-specific DNA binding; transcription factor activity
Biological Process: apoptosis; negative regulation of T cell differentiation in the thymus; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase III promoter; response to antibiotic; snRNA transcription from RNA polymerase II promoter; snRNA transcription from RNA polymerase III promoter; T cell homeostasis
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Product Notes
The ZC3H8 zc3h8 (Catalog #AAA7605838) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZC3H8 Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZC3H8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the ZC3H8 zc3h8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZC3H8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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