Zinc finger and BTB domain-containing protein 17 (Zbtb17) Recombinant Protein | Zbtb17 recombinant protein

Recombinant Mouse Zinc finger and BTB domain-containing protein 17 (Zbtb17)

Cat. Num. AAA1377456

• Gene Names: Zbtb17; Lp-1; Miz1; mZ13; Zfp100; AA589413
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Zinc finger and BTB domain-containing protein 17 (Zbtb17); Recombinant Mouse Zinc finger and BTB domain-containing protein 17 (Zbtb17); Zbtb17 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-794, Full length protein
• Sequence: MDFPQHSQRVLEQLNQQRQLGLLCDCTFVVDGVDFKAHKAVLAACSEYFKMLFVDQKDVVHLDISNAAGLGQVLEFMYTAKLSLSPENVDDVLAVASFLQMQDIVTACHTLKSLAEPSSTTGESADASAVEGGDKRAKDEKAAATMLSRLDQARGSSSTGPGRELKEERGGQAESASSGAEQTEKADAPREPPPVELKPDPTSSMAAAEAEALSESSEQEMEVEPASKGEDGQEEEGAGPATVKEEGMHLDNGEPPEENEESAGTDSGQELGMEGQNLRSGTYGDRTESKAYGSIIHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCGDCGKLFTTSGNLKRHQLVHSGQKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCTHCQRQFADPGALQRHVRIHTGEKPCQCVICGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGGEVSVVTVDDMVTLATEALAATAVTQLTVVPVGAAVTADETEVLKAEISKAVKQVQEEDPNTHILYACDSCGDKFLDANSLAQHVRIHTAQALVMFQTDADFYQQYGPGSTWPAGQMLQAGELVFRPRDGTEGQPTLAESPPTAPDCLPPAE
• Sequence Length: 794

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Zbtb17 recombinant protein

This gene encodes a zinc finger protein involved in the regulation of c-myc. The symbol MIZ1 has also been associated with PIAS2 which is a different gene located on chromosome 18.

NCBI and Uniprot Product Information

• NCBI GI #: 171919772
• NCBI GeneID: 22642
• NCBI Accession #: NP_033567.2
• NCBI GenBank Nucleotide #: NM_009541.2
• UniProt Accession #: Q60821; Q60699; A2ADB9
• Molecular Weight: 86,758 Da
• NCBI Official Full Name: zinc finger and BTB domain-containing protein 17
• NCBI Official Synonym Full Names: zinc finger and BTB domain containing 17
• NCBI Official Symbol: Zbtb17
• NCBI Official Synonym Symbols: Lp-1; Miz1; mZ13; Zfp100; AA589413
• NCBI Protein Information: zinc finger and BTB domain-containing protein 17
• UniProt Protein Name: Zinc finger and BTB domain-containing protein 17
• Protein Family: Zinc finger and BTB domain-containing protein
• UniProt Gene Name: Zbtb17
• UniProt Synonym Gene Names: Zfp100; Znf151; Zfp-100

Uniprot Description

Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Represses RB1 transcription; this repression can be blocked by interaction with ZBTB49 ().