Western Blot (WB)
(Western Blot analysis in NCI-H460 cell line lysates (35ug/lane) using MBS6007425. This demonstrates that MBS6007425 detected the ZBTB17 protein (arrow).)
Rabbit anti-Human ZBTB17 Polyclonal Antibody | anti-ZBTB17 antibody
ZBTB17, NT (ZBTB17, MIZ1, ZNF151, ZNF60, Zinc finger and BTB domain-containing protein 17, Myc-interacting zinc finger protein 1, Zinc finger protein 151, Zinc finger protein 60)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Western Blot (WB)
(Western Blot analysis in NCI-H460 cell line lysates (35ug/lane) using MBS6007425. This demonstrates that MBS6007425 detected the ZBTB17 protein (arrow).)
Western Blot (WB)
(Western Blot analysis in NCI-H460 cell line lysates (35ug/lane) using MBS6007425. This demonstrates that MBS6007425 detected the ZBTB17 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a zinc finger protein involved in the regulation of c-myc. The symbol MIZ1 has also been associated with PIAS2 which is a different gene located on chromosome 18. [provided by RefSeq, Jul 2008]
Uniprot Description
ZBTB17: May function as a housekeeping DNA-binding protein that regulates the expression of specific genes. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Also has potent growth arrest activity, probably through inhibition of cell cycle progression. Required for early embryonic development during gastrulation. Belongs to the krueppel C2H2-type zinc-finger protein family. Binds to the C-terminal helix-loop-helix motif of MYC which inhibits ZBTB17 transactivation and growth arrest activities and renders it insoluble in the nucleus. Also interacts with HCFC1, MAGEA4 and TMPRSS11A. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding; C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 1p36.13
Cellular Component: nucleoplasm
Molecular Function: protein binding; DNA binding; metal ion binding; transcription factor activity
Biological Process: cellular protein metabolic process; unfolded protein response, activation of signaling protein activity; transcription, DNA-dependent; unfolded protein response; positive regulation of transcription, DNA-dependent; ectoderm development; gastrulation with mouth forming second; negative regulation of cell cycle
Research Articles on ZBTB17
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Product Notes
The ZBTB17 zbtb17 (Catalog #AAA6007425) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZBTB17, NT (ZBTB17, MIZ1, ZNF151, ZNF60, Zinc finger and BTB domain-containing protein 17, Myc-interacting zinc finger protein 1, Zinc finger protein 151, Zinc finger protein 60) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZBTB17 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the ZBTB17 zbtb17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZBTB17, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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