YTH domain family protein 3 (Ythdf3) Recombinant Protein | Ythdf3 recombinant protein
Recombinant Mouse YTH domain family protein 3 (Ythdf3)
NCBI and Uniprot Product Information
Uniprot Description
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs and promotes RNA translation efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Shares m6A-containing mRNAs targets with YTHDF1 and YTHDF2, and regulates different processes depending on the context. Facilitates the translation of targeted mRNAs in cooperation with YTHDF1 by binding to m6A-containing mRNAs and interacting with 40S and 60S ribosome subunits. Can also act as a regulator of mRNA stability in cooperation with YTHDF2 by binding to m6A-containing mRNA and promoting their degradation. Recognizes and binds m6A-containing circular RNAs (circRNAs) and promotes their translation. circRNAs are generated through back-splicing of pre-mRNAs, a non-canonical splicing process promoted by dsRNA structures across circularizing exons.
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Product Notes
The Ythdf3 ythdf3 (Catalog #AAA1358413) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-585, Full length protein. The amino acid sequence is listed below: SATSVDQRPK GQGNKVSVQN GSIHQKDAVN DDDFEPYLSS QTNQNNSYPP MSDPYMPSYY APSIGFPYSL GEAAWSTAGD QPMPYLTTYG QMSNGEHHYI PDGVFSQPGA LGNTPPFLGQ HGFNFFPGNA DFSTWGTSGS QGQSTQNSAY SSSYGYPPSS LGRAITDGQA GFGNDTLSKV PGISSIEQGM TGLKIGGDLT AAVTKTVGTA LSSSGMTSIA TNNVPPVSSA APKPTSWAAI ARKPAKPQPK LKPKGNVGIG GSAVPPPPIK HNMNIGTWDE KGSVVKAPPT QPVLPPQTII QQPQPLIQPP PLVQSQLPQQ QPQPPQPQQQ QGPQPQAQPH QVQSQQPQLQ NRWVAPRNRG TGFNQNNGTG SENFGLGVVP VSASPSSVEV HPVLEKLKAI NNYNPKDFDW NLKNGRVFII KSYSEDDIHR SIKYSIWCST EHGNKRLDAA YRSLNGKGPL YLLFSVNGSG HFCGVAEMKS VVDYNAYAGV WSQDKWKGKF EVKWIFVKDV PNNQLRHIRL ENNDNKPVTN SRDTQEVPLE KAKQVLKIIA TFKHTTSIFD DFAHYEKRQE EEEAMRRERN RNKQ. It is sometimes possible for the material contained within the vial of "YTH domain family protein 3 (Ythdf3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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