Probable multidrug resistance ABC transporter ATP-binding/permease protein YheI (yheI) Recombinant Protein | yheI recombinant protein
Recombinant Bacillus subtilis Probable multidrug resistance ABC transporter ATP-binding/permease protein YheI (yheI)
NCBI and Uniprot Product Information
Uniprot Description
Function: Involved in the transport of four structurally unrelated drugs, including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation. Ref.4
Enzyme regulation: Inhibited by ortho-vanadate. Ref.4
Subunit structure: Heterodimer composed of YheH and YheI. Ref.4
Subcellular location: Cell membrane; Multi-pass membrane protein Ref.4.
Induction: Induced by several classes of structurally unrelated antibiotics, such as erythromycin, fusidic acid or linezolid. Ref.4
Miscellaneous: Overexpression reduces the sporulation efficiency possibly by modulating the function of KinA.
Sequence similarities: Belongs to the ABC transporter superfamily.Contains 1 ABC transmembrane type-1 domain.Contains 1 ABC transporter domain.
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Product Notes
The yheI yhei (Catalog #AAA1093310) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-585. The amino acid sequence is listed below: MFSVLKKLGW FFKAYWLRYT IAIVLLLAVN VIEMFPPKLL GNAIDDMKAG AFTAEGLLFY IGIFFVLTAA VYIMSYFWMH QLFGGANLME KILRTKLMGH LLTMSPPFYE KNRTGDLMAR GTNDLQAVSL TTGFGILTLV DSTMFMMTIF LTMGFLISWK LTFAAIIPLP VMAIAISLYG SKIHERFTEA QNAFGALNDR VLESVSGVRV IRAYVQETND VRRFNEMTAD VYQKNMKVAF IDSLFEPTVK LLVGASYLIG LGYGAFLVFR NELTLGELVS FNVYLGMMIW PMFAIGELIN VMQRGNASLD RVNETLSYET DVTDPKQPAD LKEPGDIVFS HVSFTYPSST SDNLQDISFT VRKGQTVGIA GKTGSGKTTI IKQLLRQYPP GEGSITFSGV PIQQIPLDRL RGWIGYVPQD HLLFSRTVKE NILYGKQDAT DKEVQQAIAE AHFEKDLHML PSGLETMVGE KGVALSGGQK QRISIARALM ANPEILILDD SLSAVDAKTE AAIIKNIREN RKGKTTFILT HRLSAVEHAD LILVMDGGVI AERGTHQELL ANNGWYREQY ERQQLFTAEE GGAGA. It is sometimes possible for the material contained within the vial of "Probable multidrug resistance ABC transporter ATP-binding/permease protein YheI (yheI), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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