Cytotoxic T-Lymphocyte Associated Protein 4 (CTLA4) Active Protein | CTLA4 active protein
Recombinant Guinea Pig Cytotoxic T-Lymphocyte Associated Protein 4 (CTLA4), Partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Cytotoxic T-Lymphocyte Associated Protein 4 (CTLA4); Recombinant Guinea Pig Cytotoxic T-Lymphocyte Associated Protein 4 (CTLA4); Partial; Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152; CTLA4; CTLA4 active protein
Host
Yeast
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
0.2 mum Filtered 1xPBS, pH 7.4
Sequence Positions
37-161aa; Partial
Sequence
AMHVAQPAVVLASSRGVASFECEYASSHNANEVRVTVLQQVASRTTEICAATYTVERELAFPEDSACAGTSSGTRVNLTIQGLRAADTGLYICKVELMYPPPYFVGTGNGTQIYVIDPEPCPDSD
Species
Guinea Pig
Tag
C-terminal 6xHis-tagged
Endotoxin
Less than 1.0 EU/ug as determined by LAL method.
Biological Activity
The ED50 as determined by its ability to bind Mouse B7-1 in functional ELISA is less than 0.4 ug/ml.
Classification
Drug Target
Subdivision
Immune Checkpoint
Preparation and Storage
Store at -20 degree C. For extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Related Product Information for CTLA4 active protein
Cytotoxic Tlymphocyte 4(CTLA-4, CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.
Product Categories/Family for CTLA4 active protein
NCBI and Uniprot Product Information
Similar Products
Product Notes
The CTLA4 (Catalog #AAA7115109) is an Active Protein produced from Yeast and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 37-161aa; Partial. The amino acid sequence is listed below: AMHVAQPAVV LASSRGVASF ECEYASSHNA NEVRVTVLQQ VASRTTEICA ATYTVERELA FPEDSACAGT SSGTRVNLTI QGLRAADTGL YICKVELMYP PPYFVGTGNG TQIYVIDPEP CPDSD. It is sometimes possible for the material contained within the vial of "Cytotoxic T-Lymphocyte Associated Protein 4 (CTLA4), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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