Mouse Y box binding protein 1 ELISA Kit | YBX1 elisa kit

Mouse Nuclease-sensitive element-binding protein 1, YBX1 ELISA Kit

Cat. Num. AAA9317935

• Gene Names: Ybx1; EF1A; MSY1; YB-1; dbpB; Nsep1; C79409; mYB-1a; 1700102N10Rik
• Reactivity: Mouse
• Synonyms: Y box binding protein 1; Mouse Nuclease-sensitive element-binding protein 1; YBX1 ELISA Kit; Mouse Nuclease-sensitive element-binding protein 1 (YBX1) ELISA kit; BP-8; CSDA2; CSDB; DBPB; MDR-NF1; MGC104858; MGC110976; MGC117250; NSEP-1; NSEP1; YB-1; YB1; DNA-binding protein B; major histocompatibility complex; class II; Y box-binding protein I; nuclease sensit; YBX1 elisa kit

• Reactivity: Mouse

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 113205059
• NCBI GeneID: 22608
• NCBI Accession #: NP_035862.2
• NCBI GenBank Nucleotide #: NM_011732.2
• UniProt Accession #: P62960; P22568; P27817; P43482
• Molecular Weight: 35,730 Da
• NCBI Official Full Name: nuclease-sensitive element-binding protein 1
• NCBI Official Synonym Full Names: Y box protein 1
• NCBI Official Symbol: Ybx1
• NCBI Official Synonym Symbols: EF1A; MSY1; YB-1; dbpB; Nsep1; C79409; mYB-1a; 1700102N10Rik
• NCBI Protein Information: nuclease-sensitive element-binding protein 1; CBF-A; EFI-A; DNA binding protein B; DNA-binding protein B; Y-box binding protein 1; Y-box-binding protein 1; Y-box transcription factor; enhancer factor I subunit A; nuclease sensitive element binding protein 1; CCAAT-binding transcription factor I subunit A
• UniProt Protein Name: Nuclease-sensitive element-binding protein 1
• Protein Family: Nuclease-sensitive element-binding protein
• UniProt Gene Name: Ybx1
• UniProt Synonym Gene Names: Msy-1; Msy1; Nsep1; Yb1; CBF-A; DBPB; EFI-A; YB-1
• UniProt Entry Name: YBOX1_MOUSE

Uniprot Description

YB-1: a nuclear protein that binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors CCAAT-containing Y-box of HLA class II genes. Component of cytoplasmic messenger ribonucleoprotein particles (mRNPs). Interacts with AKT1, SFRS9, THOC4, MSH2, XRCC5, WRN and NCL. Can bind to DNA as a homomeric form, (EFI-A)n or as a heteromeric form in association with EFI-B. Homodimer in the presence of ATP. Involved in cisplatin resistance. Seems to be a negative regulatory factor. May play a role in both transcriptional and translational regulation of spermatogenesis. Found at very low levels at day 10 and levels increase at day 15 and persist throughout adulthood.

Protein type: Transcription factor; RNA-binding; RNA processing; RNA splicing

Cellular Component: nuclear membrane; intracellular membrane-bound organelle; stress granule; perinuclear region of cytoplasm; dendrite; cytoplasm; extracellular region; nucleus; ribonucleoprotein complex; U12-dependent spliceosome

Molecular Function: mRNA binding; protein binding; DNA binding; nucleic acid binding; RNA binding; p53 binding; sequence-specific DNA binding; chromatin binding; transcription factor binding; single-stranded DNA binding

Biological Process: transcription from RNA polymerase II promoter; negative regulation of striated muscle cell differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; in utero embryonic development; RNA splicing; positive regulation of cell division; positive regulation of cell proliferation; negative regulation of insulin receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; mRNA processing; negative regulation of apoptosis