Human Xylosyltransferase 1 ELISA Kit | XYLT1 elisa kit
Human Xylosyltransferase 1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.[provided by RefSeq, Nov 2009]
Uniprot Description
XYLT1: Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes. Belongs to the glycosyltransferase 14 family. XylT subfamily.
Protein type: EC 2.4.2.26; Glycan Metabolism - chondroitin sulfate biosynthesis; Glycan Metabolism - heparan sulfate biosynthesis; Membrane protein, integral; Transferase
Chromosomal Location of Human Ortholog: 16p12.3
Cellular Component: Golgi membrane
Molecular Function: protein xylosyltransferase activity
Biological Process: glycosaminoglycan biosynthetic process; glycosaminoglycan metabolic process
Disease: Desbuquois Dysplasia 2; Pseudoxanthoma Elasticum
Research Articles on XYLT1
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Product Notes
The Human XYLT1 xylt1 (Catalog #AAA9426691) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9426691 ELISA Kit recognizes Human XYLT1. It is sometimes possible for the material contained within the vial of "Xylosyltransferase 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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