Human WD repeat and SOCS box-containing 1 ELISA Kit | WSB1 elisa kit

Human WD repeat and SOCS box-containing protein 1, WSB1 ELISA Kit

Cat. Num. AAA9321722

• Gene Names: WSB1; SWIP1; WSB-1
• Reactivity: Human
• Synonyms: WD repeat and SOCS box-containing 1; Human WD repeat and SOCS box-containing protein 1; WSB1 ELISA Kit; Human WD repeat and SOCS box-containing protein 1 (WSB1) ELISA kit; SWIP1; WSB-1; SOCS box-containing WD protein SWiP-1; WSB1 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: undiluted original Human body fluids, tissue homogenates, secretions or feces samples
• Assay Type: Quantitative Sandwich
• Detection Range: 3.12ng/ml-100ng/mL
• Sensitivity: 1.0ng/mL
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for WSB1 elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of WSB1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 18677720
• NCBI GeneID: 26118
• NCBI Accession #: NP_056441.6
• NCBI GenBank Nucleotide #: NM_015626.8
• UniProt Accession #: Q9Y6I7; Q9NRB1; Q9UBH9; Q9UG25; Q9UNN6; Q9Y656
• Molecular Weight: 47,432 Da
• NCBI Official Full Name: WD repeat and SOCS box-containing protein 1 isoform 1
• NCBI Official Synonym Full Names: WD repeat and SOCS box containing 1
• NCBI Official Symbol: WSB1
• NCBI Official Synonym Symbols: SWIP1; WSB-1
• NCBI Protein Information: WD repeat and SOCS box-containing protein 1; WD repeat and SOCS box-containing 1; SOCS box-containing WD protein SWiP-1
• UniProt Protein Name: WD repeat and SOCS box-containing protein 1
• Protein Family: WD repeat and SOCS box-containing protein
• UniProt Gene Name: WSB1
• UniProt Synonym Gene Names: SWIP1; WSB-1
• UniProt Entry Name: WSB1_HUMAN

NCBI Description

This gene encodes a member of the WD-protein subfamily. This protein shares a high sequence identity to mouse and chick proteins. It contains several WD-repeats spanning most of the protein and an SOCS box in the C-terminus. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

WSB1: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 17q11.1

Cellular Component: intracellular

Molecular Function: protein binding

Biological Process: protein ubiquitination