Telomerase Cajal body protein 1 (Wrap53) Recombinant Protein | Wrap53 recombinant protein
Recombinant Rat Telomerase Cajal body protein 1 (Wrap53)
Gene Names
Wrap53; Wdr79
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Telomerase Cajal body protein 1 (Wrap53); Recombinant Rat Telomerase Cajal body protein 1 (Wrap53); Wrap53 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-532, full length protein
Sequence
MKTSEELRLAPDSLPSDLVPAPVLQASPADKNTDSEPVPPPCGGDDQLQVATDAVASSVVSQELQQGDSAPLEVEFNISSELSPRIEEQEVPENASLPVEETNRPELESGEAMEGVSEEPAAVDEGDIFWSYSFSQVPQYLSGSWSEFSTRSENFLKGCKWAPDGSCILTNSADNVLRIYNLPPELYSESEQVDYAEMVPVLRMVEGDTIYDYCWYSLMSSTQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTSRPGRDCEVRTTFAKKQGQSGIISCLAFSPAQPLYACGSYGRTLGLYAWDDGSPLALLGGHQGGITHLCFHPDGNLFFSGARKDAELLCWDLRQPGHLLWSLSREVTTNQRIYFDLDPSGQFLVSGNTSGVVSVWDISGAFSDCKQLEPVMTFLPQDDCTNGVSLHPTLPLLATASGQRMFPEPTNSGDEGEPELDLPLLSLRHAHPECQLQLWWCGGGPDPSNPDEDQDEKGQGRTEAVGMS
Sequence Length
532
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
58,195 Da
NCBI Official Full Name
telomerase Cajal body protein 1
NCBI Official Synonym Full Names
WD repeat containing, antisense to TP53
NCBI Official Symbol
Wrap53
NCBI Official Synonym Symbols
Wdr79
NCBI Protein Information
telomerase Cajal body protein 1
UniProt Protein Name
Telomerase Cajal body protein 1
Protein Family
UniProt Gene Name
Wrap53
UniProt Synonym Gene Names
Tcab1; Wdr79
Uniprot Description
Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs (scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post-transcriptional level; it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage ().
Similar Products
Product Notes
The Wrap53 wrap53 (Catalog #AAA1416069) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-532, full length protein. The amino acid sequence is listed below: MKTSEELRLA PDSLPSDLVP APVLQASPAD KNTDSEPVPP PCGGDDQLQV ATDAVASSVV SQELQQGDSA PLEVEFNISS ELSPRIEEQE VPENASLPVE ETNRPELESG EAMEGVSEEP AAVDEGDIFW SYSFSQVPQY LSGSWSEFST RSENFLKGCK WAPDGSCILT NSADNVLRIY NLPPELYSES EQVDYAEMVP VLRMVEGDTI YDYCWYSLMS STQPDTSYVA SSSRENPIHI WDAFTGELRA SFRAYNHLDE LTAAHSLCFS PDGSQLFCGF NRTVRVFSTS RPGRDCEVRT TFAKKQGQSG IISCLAFSPA QPLYACGSYG RTLGLYAWDD GSPLALLGGH QGGITHLCFH PDGNLFFSGA RKDAELLCWD LRQPGHLLWS LSREVTTNQR IYFDLDPSGQ FLVSGNTSGV VSVWDISGAF SDCKQLEPVM TFLPQDDCTN GVSLHPTLPL LATASGQRMF PEPTNSGDEG EPELDLPLLS LRHAHPECQL QLWWCGGGPD PSNPDEDQDE KGQGRTEAVG MS. It is sometimes possible for the material contained within the vial of "Telomerase Cajal body protein 1 (Wrap53), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
