Proto-oncogene Wnt-3 Recombinant Protein | WNT3 recombinant protein
Recombinant mouse Proto-oncogene Wnt-3
NCBI and Uniprot Product Information
Uniprot Description
WNT3: Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube. Defects in WNT3 are the cause of autosomal recessive tetra-amelia (ARTTRA). Tetra-amelia is a rare human genetic disorder characterized by complete absence of all four limbs and other anomalies such as craniofacial, nervous system, pulmonary, skeletal and urogenital defects. Belongs to the Wnt family.
Protein type: Oncoprotein; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 11 E1|11 67.5 cM
Cellular Component: cytoplasm; extracellular space; proteinaceous extracellular matrix
Molecular Function: frizzled binding; protein binding; protein domain specific binding; receptor agonist activity; receptor binding
Biological Process: anatomical structure formation; anterior/posterior axis specification; anterior/posterior pattern formation; axon guidance; cell fate commitment; cell morphogenesis; cell-cell signaling; dorsal/ventral axis specification; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; gamete generation; limb bud formation; limb development; mesoderm formation; negative regulation of axon extension involved in axon guidance; organ morphogenesis; positive regulation of collateral sprouting in the absence of injury; positive regulation of Wnt receptor signaling pathway; regulation of neurogenesis; signal transduction; Spemann organizer formation at the anterior end of the primitive streak; Wnt receptor signaling pathway through beta-catenin
Research Articles on WNT3
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Product Notes
The WNT3 wnt3 (Catalog #AAA9420805) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full Length, 22-355aa. The Recombinant mouse Proto-oncogene Wnt-3 reacts with Mouse and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Proto-oncogene Wnt-3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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