Protein wntless homolog (WLS) Recombinant Protein | WLS recombinant protein
Recombinant Human Protein wntless homolog (WLS)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
Uniprot Description
GPR177: Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development. Belongs to the wntless family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 1p31.3
Cellular Component: cytoplasmic membrane-bound vesicle; cytoplasmic vesicle; dendrite cytoplasm; early endosome; early endosome membrane; endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane; integral to membrane; plasma membrane; trans-Golgi network
Molecular Function: mu-type opioid receptor binding; protein binding; signal transducer activity; Wnt-protein binding
Biological Process: anterior/posterior axis specification; exocrine pancreas development; hindbrain development; intracellular protein transport; mesoderm formation; midbrain development; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of Wnt receptor signaling pathway; Wnt receptor signaling pathway
Research Articles on WLS
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Product Notes
The WLS wls (Catalog #AAA7033614) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 43-541aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the WLS wls for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: VSYMSVKCVD ARKNHHKTKW FVPWGPNHCD KIRDIEEAIP REIEANDIVF SVHIPLPHME MSPWFQFMLF ILQLDIAFKL NNQIRENAEV SMDVSLAYRD DAFAEWTEMA HERVPRKLKC TFTSPKTPEH EGRYYECDVL PFMEIGSVAH KFYLLNIRLP VNEKKKINVG IGEIKDIRLV GIHQNGGFTK VWFAMKTFLT PSIFIIMVWY WRRITMMSRP PVLLEKVIFA LGISMTFINI PVEWFSIGFD WTWMLLFGDI RQGIFYAMLL SFWIIFCGEH MMDQHERNHI AGYWKQVGPI AVGSFCLFIF DMCERGVQLT NPFYSIWTTD IGTELAMAFI IVAGICLCLY FLFLCFMVFQ VFRNISGKQS SLPAMSKVRR LHYEGLIFRF KFLMLITLAC AAMTVIFFIV SQVTEGHWKW GGVTVQVNSA FFTGIYGMWN LYVFALMFLY APSHKNYGED QSNGDLGVHS GEELQLTTTI THVDGPTEIY KLTRKEAQE. It is sometimes possible for the material contained within the vial of "Protein wntless homolog (WLS), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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