Human WD repeat domain 79 ELISA Kit | WDR79 elisa kit
Human Telomerase Cajal body protein 1, WDR79 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq, Mar 2011]
Uniprot Description
WRAP53: a protein of unknown function. Contains 6 WD40 domains, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly.
Chromosomal Location of Human Ortholog: 17p13.1
Cellular Component: nucleoplasm; Cajal body; telomerase holoenzyme complex; cytoplasm; nucleus
Molecular Function: protein binding; RNA binding
Biological Process: telomere formation via telomerase; positive regulation of telomerase activity
Disease: Dyskeratosis Congenita, Autosomal Recessive, 3
Research Articles on WDR79
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Product Notes
The Human WDR79 wrap53 (Catalog #AAA9324769) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9324769 ELISA Kit recognizes Human WDR79. It is sometimes possible for the material contained within the vial of "WD repeat domain 79, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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