Mouse vacuolar protein sorting 4 homolog B (S. cerevisiae) ELISA Kit | VPS4B elisa kit
Mouse Vacuolar protein sorting-associated protein 4B, VPS4B ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
VPS4B: Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Belongs to the AAA ATPase family.
Protein type: EC 3.6.4.6; Vesicle
Cellular Component: spindle pole; centrosome; membrane; lysosome; vacuolar membrane; early endosome; late endosome; cytoplasm; endosome membrane; cytosol; nucleus; endosome
Molecular Function: protein C-terminus binding; protein binding; hydrolase activity; ATPase activity; nucleotide binding; ATPase activity, coupled; ATP binding
Biological Process: cholesterol transport; cell separation during cytokinesis; ubiquitin-dependent protein catabolic process via the multivesicular body pathway; endosome organization and biogenesis; regulation of viral reproduction; intracellular cholesterol transport; response to lipid; protein depolymerization; cell cycle; endosome transport; mitotic metaphase plate congression; endosome to lysosome transport via multivesicular body sorting pathway; protein transport; cell division; transport; potassium ion transport; nuclear organization and biogenesis; vacuole organization and biogenesis
Research Articles on VPS4B
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Product Notes
The Mouse VPS4B vps4b (Catalog #AAA9337745) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9337745 ELISA Kit recognizes Mouse VPS4B. It is sometimes possible for the material contained within the vial of "vacuolar protein sorting 4 homolog B (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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