Human vacuolar protein sorting 37 homolog C (S. cerevisiae) ELISA Kit | VPS37C elisa kit

Human Vacuolar protein sorting-associated protein 37C, VPS37C ELISA Kit

Cat. Num. AAA9328857

• Reactivity: Human
• Synonyms: vacuolar protein sorting 37 homolog C (S. cerevisiae); Human Vacuolar protein sorting-associated protein 37C; VPS37C ELISA Kit; Human Vacuolar protein sorting-associated protein 37C (VPS37C) ELISA kit; FLJ20847; vacuolar protein sorting 37C; VPS37C elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Assay Type: Quantitative Sandwich
• Detection Range: 31.2pg/ml-1000pg/ml
• Sensitivity: 5.0pg/ml
• Intra-assay Precision: Intra-assay CV(%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for VPS37C elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of VPS37C (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 57863314
• NCBI GeneID: 55048
• NCBI Accession #: NP_060436.4
• NCBI GenBank Nucleotide #: NM_017966.4
• UniProt Accession #: A5D8V6; Q8N3K4
• Molecular Weight: 38,659 Da
• NCBI Official Full Name: vacuolar protein sorting-associated protein 37C
• NCBI Official Synonym Full Names: vacuolar protein sorting 37 homolog C (S. cerevisiae)
• NCBI Official Symbol: VPS37C
• NCBI Protein Information: vacuolar protein sorting-associated protein 37C; hVps37C; vacuolar protein sorting 37C; ESCRT-I complex subunit VPS37C
• UniProt Protein Name: Vacuolar protein sorting-associated protein 37C
• Protein Family: Vacuolar protein sorting-associated protein
• UniProt Gene Name: VPS37C
• UniProt Synonym Gene Names: PML39; hVps37C
• UniProt Entry Name: VP37C_HUMAN

NCBI Description

VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).[supplied by OMIM, Mar 2008]

Uniprot Description

VPS37C: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. Belongs to the VPS37 family.

Chromosomal Location of Human Ortholog: 11q12.2

Cellular Component: late endosome membrane; endosome membrane

Molecular Function: protein binding; calcium-dependent protein binding

Biological Process: protein transport; viral reproduction; viral protein processing; viral infectious cycle; virus assembly; endosome transport