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Virion membrane protein A14 (A14L) Recombinant Protein

Recombinant Vaccinia virus Virion membrane protein A14 (A14L)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Virion membrane protein A14 (A14L); Recombinant Vaccinia virus Virion membrane protein A14 (A14L); Recombinant Virion membrane protein A14 (A14L); Virion membrane protein A14; Virion membrane protein A14 (A14L) recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-90
Sequence
MDMMLMIGNYFSGVLIAGIILLILSCIFAFIDFSKSTSPTRTWKVLSIMAFILGIIITVGMLIYSMWGKHCAPHRVSGVIHTNHSDISMN
Sequence Length
90
Species
Vaccinia virus (strain Copenhagen) (VACV)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
9,994 Da
NCBI Official Full Name
Virion membrane protein A14
UniProt Protein Name
Virion membrane protein A14
UniProt Entry Name
A14_VACCC

Uniprot Description

Function: Envelope protein which is a major component of the mature virion (MV) membrane. Essential for membrane biogenesis. Is required, together with A17, to form bona fide crescents, which can progress to form the immature virion (IV) membrane. A14 and A17 form a lattice that is stabilized by disulfide bonds and serves as an anchor within the viral membrane to which several other proteins important in virion structure and morphogenesis attach

By similarity.

Subunit structure: Homodimer; disulfide-linked

By similarity. Interacts with A17

By similarity.

Subcellular location: Virion membrane; Multi-pass membrane protein

Potential. Note: Component of the mature virion (MV) membrane

By similarity.

Post-translational modification: Phosphorylated by viral F10 kinase, phosphorylation state is regulated by H1 phosphatase

By similarity.

Sequence similarities: Belongs to the chordopoxvirinae A14 family.

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Product Notes

The Virion membrane protein A14 (A14L) (Catalog #AAA1152556) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-90. The amino acid sequence is listed below: MDMMLMIGNY FSGVLIAGII LLILSCIFAF IDFSKSTSPT RTWKVLSIMA FILGIIITVG MLIYSMWGKH CAPHRVSGVI HTNHSDISMN. It is sometimes possible for the material contained within the vial of "Virion membrane protein A14 (A14L), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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