Synaptobrevin-1 Recombinant Protein | VAMP1 recombinant protein

Recombinant Human Synaptobrevin-1

Gene Names

VAMP1; SYB1; SPAX1; VAMP-1

Purity

Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Synonyms

Synaptobrevin-1; Recombinant Human Synaptobrevin-1; VAMP1 Human; Synaptobrevin-1 Human Recombinant; Vesicle-associated membrane protein 1; SYB1; VAMP-1; VAMP1; DKFZp686H12131; VAMP1 recombinant protein

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Cat. Num. AAA143127 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Host

E Coli

Purity/Purification

Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Form/Format

The protein solution (1mg/ml) contains 1X PBS and 1mM EDTA.
Sterile Filtered colorless solution.

Sequence

MGSSHHHHHH SSGLVPRGSH MSAPAQPPAE GTEGTAPGGG PPGPPPNMTS NRRLQQTQAQVEEVVDIIRV NVDKVLERDQ KLSELDDRAD ALQAGASQFE SSAAKLKRKY W

Sequence Length

116

Related Product Information for VAMP1 recombinant protein

Description: VAMP1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 111 amino acids and having a molecular mass of 11.9 kDa.

Introduction: Synaptobrevin 1(Vehicle-associated membrane, VAMP1) is one of the key proteins in the SNARE complex which is involved in regulated exocytosis. Synaptobrevin1 binds to t-SNAREs, syntaxin (STX) and SNAP25, after the fusion of synaptic vesicles to plasma membrane.

Product Categories/Family for VAMP1 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Synaptobrevin

NCBI and Uniprot Product Information

NCBI GI #

662033932

NCBI GeneID

6843

NCBI Accession #

NP_001284367.1

NCBI GenBank Nucleotide #

NM_001297438.1

UniProt Accession #

P23763; O75468; Q15857; Q6FG94; Q8IVC9; A8MVP3; D3DUR3

Molecular Weight

12,658 Da

NCBI Official Full Name

vesicle-associated membrane protein 1 isoform 4

NCBI Official Synonym Full Names

vesicle-associated membrane protein 1 (synaptobrevin 1)

NCBI Official Symbol

VAMP1

NCBI Official Synonym Symbols

SYB1; SPAX1; VAMP-1

NCBI Protein Information

vesicle-associated membrane protein 1; synaptobrevin 1; synaptobrevin-1

UniProt Protein Name

Vesicle-associated membrane protein 1

Protein Family

Synaptobrevin

UniProt Gene Name

VAMP1

UniProt Synonym Gene Names

SYB1; VAMP-1

UniProt Entry Name

VAMP1_HUMAN

NCBI Description

Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014]

Uniprot Description

VAMP1: Involved in the targeting and/or fusion of transport vesicles to their target membrane. Belongs to the synaptobrevin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p

Cellular Component: SNARE complex; synaptic vesicle; mitochondrial outer membrane; neuron projection; cell surface; synaptic vesicle membrane; integral to plasma membrane; cell junction; cytosol

Molecular Function: SNAP receptor activity; SNARE binding; protein binding

Biological Process: vesicle fusion; exocytosis; pathogenesis

Disease: Spastic Ataxia 1, Autosomal Dominant

Research Articles on VAMP1

1. This report identifies vesicle-associated membrane protein 1 (VAMP1), which encodes a critical protein for synaptic exocytosis, as the responsible gene fora dominantly inherited spastic ataxia

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Product Notes

The VAMP1 vamp1 (Catalog #AAA143127) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MSAPAQPPAE GTEGTAPGGG PPGPPPNMTS NRRLQQTQAQ VEEVVDIIRV NVDKVLERDQ KLSELDDRAD ALQAGASQFE SSAAKLKRKY W. It is sometimes possible for the material contained within the vial of "Synaptobrevin-1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.