Human ubiquitously transcribed tetratricopeptide repeat, X chromosome ELISA Kit | UTX elisa kit

Human Lysine-specific demethylase 6A, UTX ELISA Kit

Cat. Num. AAA9327158

• Gene Names: KDM6A; UTX; KABUK2; bA386N14.2
• Reactivity: Human
• Synonyms: ubiquitously transcribed tetratricopeptide repeat; X chromosome; Human Lysine-specific demethylase 6A; UTX ELISA Kit; Human Lysine-specific demethylase 6A (UTX) ELISA kit; RP13-886N14.3; DKFZp686A03225; MGC141941; UTX; bA386N14.2; bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX) ) ; ubiquitously-transcribed TPR gene on the X chromo; UTX elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Camel Body Fluids And Tissue Homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 1.56nmol/L-50nmol/L
• Sensitivity: 0.1nmol/L.
• Intra-assay Precision: Intra-assay CV (%)is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for UTX elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used for determine the level of U-T4 (hereafter termed "analyte") in undiluted original Camel body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 189011544
• NCBI GeneID: 7403
• NCBI Accession #: NP_066963.2
• NCBI GenBank Nucleotide #: NM_021140.3
• UniProt Accession #: O15550; Q52LL9; Q5JVQ7
• Molecular Weight: 154,177 Da
• NCBI Official Full Name: lysine-specific demethylase 6A isoform 3
• NCBI Official Synonym Full Names: lysine (K)-specific demethylase 6A
• NCBI Official Symbol: KDM6A
• NCBI Official Synonym Symbols: UTX; KABUK2; bA386N14.2
• NCBI Protein Information: lysine-specific demethylase 6A; histone demethylase UTX; ubiquitously-transcribed TPR gene on the X chromosome; ubiquitously transcribed tetratricopeptide repeat protein X-linked; bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX))
• UniProt Protein Name: Lysine-specific demethylase 6A
• UniProt Gene Name: KDM6A
• UniProt Synonym Gene Names: UTX
• UniProt Entry Name: KDM6A_HUMAN

NCBI Description

This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]

Uniprot Description

UTX: a nuclear protein that contains 8 tetratrico peptide repeat (TPRs). Processes involving TPR proteins include cell-cycle control, transcription repression, stress response, protein kinase inhibition, mitochondrial and peroxisomal protein transport and neurogenesis.

Protein type: EC 1.14.11.-; Oxidoreductase

Chromosomal Location of Human Ortholog: Xp11.2

Cellular Component: nucleoplasm; histone methyltransferase complex; nucleus

Molecular Function: identical protein binding; dioxygenase activity; metal ion binding

Biological Process: heart morphogenesis; notochord morphogenesis; respiratory system process; establishment and/or maintenance of chromatin architecture; regulation of gene expression; in utero embryonic development; multicellular organism growth; histone H3-K4 methylation; neural tube closure; mesodermal cell differentiation; Wnt receptor signaling pathway through beta-catenin; somite rostral/caudal axis specification

Disease: Kabuki Syndrome 2; Kabuki Syndrome 1