Western Blot (WB)
(All lanes : Anti-KDM6A Antibody (Center) at 1:2000 dilutionLane 1: human liver lysatesLane 2: Hela whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 154 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit anti-Human KDM6A Polyclonal Antibody | anti-KDM6A antibody
KDM6A Antibody (Center)
Western Blot (WB)
(All lanes : Anti-KDM6A Antibody (Center) at 1:2000 dilutionLane 1: human liver lysatesLane 2: Hela whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 154 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(All lanes : Anti-KDM6A Antibody (Center) at 1:2000 dilutionLane 1: human liver lysatesLane 2: Hela whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 154 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Ross M.T.,et al.Nature 434:325-337(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Cho Y.-W.,et al.J. Biol. Chem. 282:20395-20406(2007).
Lan F.,et al.Nature 449:689-694(2007).
NCBI and Uniprot Product Information
NCBI Description
This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]
Uniprot Description
UTX: a nuclear protein that contains 8 tetratrico peptide repeat (TPRs). Processes involving TPR proteins include cell-cycle control, transcription repression, stress response, protein kinase inhibition, mitochondrial and peroxisomal protein transport and neurogenesis.
Protein type: EC 1.14.11.-; Oxidoreductase
Chromosomal Location of Human Ortholog: Xp11.2
Cellular Component: nucleoplasm; histone methyltransferase complex; nucleus
Molecular Function: identical protein binding; dioxygenase activity; metal ion binding
Biological Process: heart morphogenesis; respiratory system process; notochord morphogenesis; establishment and/or maintenance of chromatin architecture; regulation of gene expression; in utero embryonic development; multicellular organism growth; neural tube closure; histone H3-K4 methylation; mesodermal cell differentiation; Wnt receptor signaling pathway through beta-catenin; somite rostral/caudal axis specification
Disease: Kabuki Syndrome 2; Kabuki Syndrome 1
Research Articles on KDM6A
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Product Notes
The KDM6A kdm6a (Catalog #AAA9201376) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KDM6A Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KDM6A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:2000. Researchers should empirically determine the suitability of the KDM6A kdm6a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KDM6A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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