Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X) Recombinant Protein | USP9X recombinant protein

Recombinant Human Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X) , partial

• Gene Names: USP9X; FAF; FAM; DFFRX; MRX99; MRXS99F
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X); Recombinant Human Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X); partial; USP9X recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 2,554

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for USP9X recombinant protein

This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

NCBI and Uniprot Product Information

• NCBI GI #: 145309309
• NCBI GeneID: 8239
• NCBI Accession #: NP_001034679.2
• NCBI GenBank Nucleotide #: NM_001039590.2
• UniProt Accession #: Q93008; O75550; Q8WWT3; Q8WX12
• Molecular Weight: 290,463 Da
• NCBI Official Full Name: probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform 3
• NCBI Official Synonym Full Names: ubiquitin specific peptidase 9, X-linked
• NCBI Official Symbol: USP9X
• NCBI Official Synonym Symbols: FAF; FAM; DFFRX; MRX99; MRXS99F
• NCBI Protein Information: probable ubiquitin carboxyl-terminal hydrolase FAF-X
• UniProt Protein Name: Probable ubiquitin carboxyl-terminal hydrolase FAF-X
• Protein Family: Probable ubiquitin carboxyl-terminal hydrolase
• UniProt Gene Name: USP9X
• UniProt Synonym Gene Names: DFFRX; FAM; USP9; hFAM

NCBI Description

This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Uniprot Description

Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration.