Ubiquitin carboxyl-terminal hydrolase 30 (Usp30) Recombinant Protein | Usp30 recombinant protein
Recombinant Mouse Ubiquitin carboxyl-terminal hydrolase 30 (Usp30), partial
Gene Names
Usp30; AI851327; D5Ertd483e; 6330590F17Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Ubiquitin carboxyl-terminal hydrolase 30 (Usp30); Recombinant Mouse Ubiquitin carboxyl-terminal hydrolase 30 (Usp30); partial; Usp30 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
57-517
Sequence
TERK KRRKGLVPGL VNLGNTCFMN SLLQGLSACP AFVKWLEEFT TQYSRDQQGP HTHQCLSLTL LNLLKALSCQ EVTEDEVLDA SCLLDVLRMY RWQISSFEEQ DAHELFHVIT SSLEDERDRQ PRVTHLFDVH SLEQQSEMAP RQVTCHTRGS PHPTTNHWKS QHPFHGRLTS NMVCKHCEHQ SPVRFDTFDS LSLSIPAATW GHPLTLDHCL HHFISSESVR DVVCDNCTKI EARGTLTGEK VEHQRSTFVK QLKLGKLPQC LCIHLQRLSW SSHGTPLKRH EHVQFNEFLM MDFYKYRLLG HKPSQHGPKA TENPGSAPEV QDAQAAPKPG LSQPGAPKTQ IFLNGACSPS LLPALPSPVA FPLPVVPDYS SSTYLFRLMA VVVHHGDMHS GHFVTYRRSP PSAKNPLSTS NQWLWISDDT VRKASLQEVL SSSAYLLFYE RVLSRVQQQG REYRSEE
Sequence Length
461
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
58,221 Da
NCBI Official Full Name
ubiquitin carboxyl-terminal hydrolase 30
NCBI Official Synonym Full Names
ubiquitin specific peptidase 30
NCBI Official Symbol
Usp30
NCBI Official Synonym Symbols
AI851327; D5Ertd483e; 6330590F17Rik
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase 30
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 30
Protein Family
UniProt Gene Name
Usp30
UniProt Synonym Gene Names
Ub-specific protease 30
Uniprot Description
Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin's ability to drive mitophagy. Preferentially cleaves 'Lys-6'- and 'Lys-11'-linked polyubiquitin chains, 2 types of linkage that participate in mitophagic signaling. Does not cleave efficiently polyubiquitin phosphorylated at 'Ser-65' (). Acts as negative regulator of mitochondrial fusion by mediating deubiquitination of MFN1 and MFN2 (PubMed:24513856).
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Product Notes
The Usp30 usp30 (Catalog #AAA1357425) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 57-517. The amino acid sequence is listed below: TERK KRRKGLVPGL VNLGNTCFMN SLLQGLSACP AFVKWLEEFT TQYSRDQQGP HTHQCLSLTL LNLLKALSCQ EVTEDEVLDA SCLLDVLRMY RWQISSFEEQ DAHELFHVIT SSLEDERDRQ PRVTHLFDVH SLEQQSEMAP RQVTCHTRGS PHPTTNHWKS QHPFHGRLTS NMVCKHCEHQ SPVRFDTFDS LSLSIPAATW GHPLTLDHCL HHFISSESVR DVVCDNCTKI EARGTLTGEK VEHQRSTFVK QLKLGKLPQC LCIHLQRLSW SSHGTPLKRH EHVQFNEFLM MDFYKYRLLG HKPSQHGPKA TENPGSAPEV QDAQAAPKPG LSQPGAPKTQ IFLNGACSPS LLPALPSPVA FPLPVVPDYS SSTYLFRLMA VVVHHGDMHS GHFVTYRRSP PSAKNPLSTS NQWLWISDDT VRKASLQEVL SSSAYLLFYE RVLSRVQQQG REYRSEE. It is sometimes possible for the material contained within the vial of "Ubiquitin carboxyl-terminal hydrolase 30 (Usp30), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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