Upregulator Of Cell Proliferation Recombinant Protein | URGCP recombinant protein

Recombinant Upregulator Of Cell Proliferation (URGCP)

Cat. Num. AAA2028868

• Gene Names: URGCP; URG4
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: >95%
• Synonyms: Upregulator Of Cell Proliferation; Recombinant Upregulator Of Cell Proliferation (URGCP); URGCP recombinant protein

• Host: Host: E Coli; Source: Prokaryotic expression
• Purity/Purification: >95%
• Form/Format: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Sequence: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.; RS RLVVLSALGV PGTGKSTLLN TMFGLKFATG RSCSPRGAFM QLLPVAEGFS QDLGCDQILV IDSGGLISGA LASAGDRFEL EASLATLLMG LSNVTVVSLA ETKDIPPAVL HAFLRLEKMG HMPNYQFVYQ NLHDLPVPSP KPRDRRQLLD PPSDLSRATH LEKQGGGFRT LAGLAERQHV WHIPALWHGA PPMAAVSLGY SEAIFELKRC LLENIRNGLS NQNQNIQQLIELLR
• Sequence Length: 888

• Applicable Applications for URGCP recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Predicted Molecular Mass: 29.4kDa
• Accurate Molecular Mass (KD): 29kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Expression System: Prokaryotic expression
• Tag: N-terminal His-Tag, T7 tag
• Organism Species: Mus musculus (Mouse)
• Fragment: Asp46~Glu339
• Usage: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 586946374
• NCBI GeneID: 55665
• NCBI Accession #: NP_001277004.1
• NCBI GenBank Nucleotide #: NM_001290075.1
• Molecular Weight: 100,373 Da
• NCBI Official Full Name: up-regulator of cell proliferation isoform 2
• NCBI Official Synonym Full Names: upregulator of cell proliferation
• NCBI Official Symbol: URGCP
• NCBI Official Synonym Symbols: URG4
• NCBI Protein Information: up-regulator of cell proliferation
• UniProt Protein Name: Up-regulator of cell proliferation
• Protein Family: Up-regulator of cell proliferation
• UniProt Gene Name: URGCP
• UniProt Entry Name: URGCP_HUMAN

NCBI Description

URG4 is upregulated in the presence of hepatitis B virus (HBV)-encoded X antigen (HBxAg) and may contribute to the development of hepatocellular carcinoma by promoting hepatocellular growth and survival (Tufan et al., 2002 [PubMed 12082552]).[supplied by OMIM, Mar 2008]

Uniprot Description

URG4: May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. May play an important role in development of gastric cancer. Induced by HBxAg. Up-regulated in gastric cancer tissues and also in gastric cancer cell lines (at protein level). 3 human isoforms produced by alternative splicing.

Chromosomal Location of Human Ortholog: 7p13

Cellular Component: cytoplasm; nucleus

Molecular Function: GTP binding

Biological Process: cell cycle