Uniprot Description
Function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
By similarity. HAMAP-Rule MF_01006
Catalytic activity: Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006
Subcellular location: Cell inner membrane; Multi-pass membrane protein
By similarity HAMAP-Rule MF_01006.
Miscellaneous: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available. HAMAP-Rule MF_01006
Sequence similarities: Belongs to the UppP family.
Product Notes
The Aave_2042 uppp (Catalog #
AAA1010718) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-274. The amino acid sequence is listed below: MDFILLAKAA VMGVVEGLTE FLPVSSTGHL ILAGALLGFD DDKAKVFDIA IQTGAIFAVV LVYWQKIRET LVALPTQPRA RRFALNVLIG FLPAVVLALI FGKAIKAHLF TPVVVASTFI LGGFVILWAE RRAPGAVRVD SVDDMTPLDA LKVGLVQCLA MVPGTSRSGA TIIGGMLLGL SRKAATDFSF FLAIPTLIGA GVYSLYKERH LLSMADLPLF AVGLLFSFVS AWLCVRWLLR YISTHSFVPF AYYRIAFGIV VLATAWTGWV HWGE.
It is sometimes possible for the material contained within the vial of
"Undecaprenyl-diphosphatase (uppP), Recombinant Protein" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech
cannot be held
responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any
aspect of this datasheet at
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