SDS-Page
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
UNC5H2/UNC5B recombinant protein
Recombinant Rat UNC5H2/UNC5B protein
Applications
SDS-Page
Purity
>90% by SDS-PAGE
Synonyms
UNC5H2/UNC5B; Recombinant Rat UNC5H2/UNC5B protein; unc-5 netrin receptor B; Unc5h2; unc-5 homolog 2; Protein unc-5 homolog B; netrin receptor UNC5B precursor; netrin receptor UNC5B; protein unc-5 homolog 2; unc5b; UNC5H2/UNC5B recombinant protein
Host
HEK293
Purity/Purification
>90% by SDS-PAGE
Form/Format
Liquid. In Phosphate-Buffered Saline (pH7.4) containing 10% glycerol
Concentration
0.25mg/ml (determined by Absorbance at 280nm) (varies by lot)
Sequence Positions
27-373aa
Sequence
Applicable Applications for UNC5H2/UNC5B recombinant protein
SDS-PAGE
Endotoxin
<1 EU per 1ug of protein (determined by LAL method)
Species
Rat
Tag
hIgG-His-Tag
Predicted N-term
Asp
Preparation and Storage
Can be stored at +2C to +8 degree C for 1 week. For long term storage, aliquot and store at -20C to -80 degree C. Avoid repeated freezing and thawing cycles.
SDS-Page
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
SDS-Page
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
Related Product Information for UNC5H2/UNC5B recombinant protein
UNC5B/UNC5B, also known as Netrin receptor UNC5B, is one of four related receptors that comprise the UNC5 family and serve as receptors for the axon guidance molecule Netrin-1. Outside of the nervous system, UNC5B facilitates Netrin-1-mediated inhibition of capillary branching and leukocyte migration, as well as Netrin-1-mediated promotion of osteoclast differentiation. Also this protein activates DAPK1 which mediates apoptosis. It is believed to play a role in tumorgenesis. Additionally, It is thought to play a critical role in the development of atherosclerosis and the survival of renal tubular epithelial cells during acute kidney injury. Recombinant Rat UNC5B/UNC5B, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.
Product Categories/Family for UNC5H2/UNC5B recombinant protein
References
Bhat SA, et al, (2019) J Cell Commun Signal. 13:121-127. Mediero A, et al, (2016) FASEB J. 30:3835-3844. Liu J, et al, (2013) Tumour Biol. 34:2099-2108.
NCBI and Uniprot Product Information
UniProt Accession #
Molecular Weight
66.0kDa (590aa)
UniProt Protein Name
Netrin receptor UNC5B
UniProt Gene Name
Unc5b
UniProt Synonym Gene Names
Unc5h2
UniProt Entry Name
UNC5B_RAT
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Product Notes
The UNC5H2/UNC5B unc5b (Catalog #AAA201264) is a Recombinant Protein produced from HEK293 and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 27-373aa. AAA Biotech's UNC5H2/UNC5B can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the UNC5H2/UNC5B unc5b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below:Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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