Calcium Dependent Secretion Activator Recombinant Protein | CADPS recombinant protein

Recombinant Calcium Dependent Secretion Activator (CADPS)

Cat. Num. AAA2034475

• Reactivity: Human
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: >90%
• Synonyms: Calcium Dependent Secretion Activator; Recombinant Calcium Dependent Secretion Activator (CADPS); CAPS; CAPS1; Calcium-dependent activator protein for secretion 1; CADPS recombinant protein

• Host: E Coli
• Reactivity: Human
• Purity/Purification: >90%
• Sequence Length: 17

• Applicable Applications for CADPS recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Fragment: Val1186~Asp1352
• Tag: Two N-terminal Tags, His-tag and GST-tag
• Expression System: Prokaryotic Expression
• Preparation and Storage: Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 392901307
• NCBI GeneID: 178233
• NCBI Accession #: NP_001255671.1
• NCBI GenBank Nucleotide #: NM_001268742.1
• Molecular Weight: 49.2kDa
• NCBI Official Full Name: Calcium-dependent secretion activator
• NCBI Official Symbol: unc-31
• NCBI Protein Information: Calcium-dependent secretion activator; hypothetical protein
• UniProt Protein Name: Calcium-dependent secretion activator
• Protein Family: Calcium-dependent secretion activator
• UniProt Gene Name: unc-31
• UniProt Entry Name: CAPS_CAEEL

Uniprot Description

Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. May specifically mediate the Ca2+-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (). Specifically required to activate the neuronal G-alpha pathway. Functions with G-alpha proteins from the same motor neurons to regulate locomotion (PubMed:16272411). Involved in regulating entry into quiescence triggered by satiety (PubMed:18316030). Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 and upstream of innexin unc-7 and egl-4/PKG in ALA neurons, involved in the decrease in pharyngeal pumping during the quiescent state that precedes each larval molt (PubMed:17891142). Plays a role in octopamine signaling and specifically, the octopamine inhibition of aversion responses in olfactory sensory neurons (PubMed:22124329).