Ubiquitin-like-specific protease 1A (ULP1A) Recombinant Protein | ULP1A recombinant protein

Recombinant Arabidopsis thaliana Ubiquitin-like-specific protease 1A (ULP1A) , partial

• Gene Names: ULP1A; AtULP1a; ELS1; ESD4-LIKE SUMO PROTEASE 1; UB-like protease 1A
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Ubiquitin-like-specific protease 1A (ULP1A); Recombinant Arabidopsis thaliana Ubiquitin-like-specific protease 1A (ULP1A); partial; ULP1A recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 502

• Species: Arabidopsis thaliana (Mouse-ear cress)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 30680058
• NCBI GeneID: 819876
• NCBI Accession #: NP_187347.2
• NCBI GenBank Nucleotide #: NM_111571.3
• UniProt Accession #: Q8GYL3; Q9M908
• Molecular Weight: 58,169 Da
• NCBI Official Full Name: UB-like protease 1A
• NCBI Official Symbol: ULP1A
• NCBI Official Synonym Symbols: AtULP1a; ELS1; ESD4-LIKE SUMO PROTEASE 1; UB-like protease 1A
• NCBI Protein Information: UB-like protease 1A
• UniProt Protein Name: Ubiquitin-like-specific protease 1A
• Protein Family: Ubiquitin-like-specific protease
• UniProt Gene Name: ULP1A

NCBI Description

Encodes a deSUMOylating enzyme. In vitro it has both peptidase activity and isopeptidase activity: it can cleave the C-terminal residues from SUMO to activate it for attachment to a target protein and it can also act on the isopeptide bond between SUMO and another protein. In vitro assays suggest that this enzyme is active against SUMO1 and SUMO2. It has weak activity with SUMO3 and cannot act on SUMO5. The N-terminal regulatory region of this protein is required for full activity.

Uniprot Description

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMOs to their mature forms and deconjugation of SUMO from targeted proteins. Cleaves precursors of SUM1 and SUM2, and very inefficiently of SUM3. Seems to be the only ULP1 able to cleave SUM3 precursors. Cleaves SUMO peptides better than SUMO-conjugated proteins.