Mouse UDP glucuronosyltransferase 1 family, polypeptide A1 ELISA Kit | UGT1A1 elisa kit
Mouse UDP-glucuronosyltransferase 1-1, UGT1A1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
UGT1A1: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX- alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Is also able to catalyze the glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4- methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone. Part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX. Expressed in liver. Not expressed in skin or kidney. Belongs to the UDP-glycosyltransferase family. 1 isoforms of the human protein are produced by alternative splicing.
Protein type: Transferase; Cofactor and Vitamin Metabolism - retinol; Membrane protein, integral; Carbohydrate Metabolism - ascorbate and aldarate; Carbohydrate Metabolism - starch and sucrose; Lipid Metabolism - androgen and estrogen; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Xenobiotic Metabolism - drug metabolism - other enzymes; Xenobiotic Metabolism - metabolism by cytochrome P450; Xenobiotic Metabolism - drug metabolism - cytochrome P450; EC 2.4.1.17; Carbohydrate Metabolism - pentose and glucuronate interconversions
Cellular Component: endoplasmic reticulum membrane; membrane; intracellular membrane-bound organelle; integral to plasma membrane; endoplasmic reticulum; integral to membrane
Molecular Function: transferase activity; enzyme inhibitor activity; transferase activity, transferring glycosyl groups; enzyme binding; retinoic acid binding; protein homodimerization activity; transferase activity, transferring hexosyl groups; protein heterodimerization activity; glucuronosyltransferase activity; steroid binding
Biological Process: response to organic substance; flavonoid biosynthetic process; metabolic process; negative regulation of catalytic activity; flavone metabolic process; cellular response to hormone stimulus
Research Articles on UGT1A1
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Product Notes
The Mouse UGT1A1 ugt1a1 (Catalog #AAA9323596) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9323596 ELISA Kit recognizes Mouse UGT1A1. It is sometimes possible for the material contained within the vial of "UDP glucuronosyltransferase 1 family, polypeptide A1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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