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Typical Testing Data/Standard Curve (for reference only)

Human urocortin 2 ELISA Kit | UCN2 elisa kit

Human Urocortin-2, UCN2 ELISA Kit

Gene Names
UCN2; UR; SRP; URP; UCNI; UCN-II
Reactivity
Human
Synonyms
urocortin 2; Human Urocortin-2; UCN2 ELISA Kit; Human Urocortin-2 (UCN2) ELISA kit; SRP; UCN-II; UCNI; UR; URP; stresscopin-related peptide; urocortin II; urocortin-related peptide; UCN2 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of human ucMGP. No significant cross-reactivity or interference between human ucMGP and analogues was observed.
Sequence Length
112
Samples
Serum, Plasma
Assay Type
Quantitative Sandwich
Detection Range
0.156 ng/ml-10 ng/ml
Sensitivity
0.039 ng/ml.
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess
Inter-assay Precision
Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for UCN2 elisa kit
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ucMGP has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ucMGP present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ucMGP is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ucMGP bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
12,146 Da
NCBI Official Full Name
urocortin-2 preproprotein
NCBI Official Synonym Full Names
urocortin 2
NCBI Official Symbol
UCN2
NCBI Official Synonym Symbols
UR; SRP; URP; UCNI; UCN-II
NCBI Protein Information
urocortin-2; ucn II; urocortin II; prepro-urocortin 2; urocortin-related peptide; stresscopin-related peptide
UniProt Protein Name
Urocortin-2
Protein Family
UniProt Gene Name
UCN2
UniProt Synonym Gene Names
SRP; URP; Ucn II
UniProt Entry Name
UCN2_HUMAN

NCBI Description

This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq, Jul 2008]

Uniprot Description

UCN2: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress. Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: extracellular space; extracellular region

Molecular Function: hormone binding; G-protein-coupled receptor binding; hormone activity; corticotropin-releasing hormone receptor 2 binding; receptor binding

Biological Process: negative regulation of luteinizing hormone secretion; cell proliferation; cellular response to nutrient levels; digestion; response to stress; cAMP biosynthetic process; G-protein signaling, adenylate cyclase activating pathway; negative regulation of follicle-stimulating hormone secretion

Research Articles on UCN2

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Product Notes

The Human UCN2 ucn2 (Catalog #AAA923385) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA923385 ELISA Kit recognizes Human UCN2. It is sometimes possible for the material contained within the vial of "urocortin 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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