Mouse U2 small nuclear RNA auxiliary factor 2 ELISA Kit | U2AF2 elisa kit
Mouse Splicing factor U2AF 65 kDa subunit, U2AF2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
U2AF2: Necessary for the splicing of pre-mRNA. Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Represses the splicing of MAPT/Tau exon 10. Belongs to the splicing factor SR family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; RNA splicing; Spliceosome
Cellular Component: nucleoplasm; spliceosome; nuclear speck; nucleus
Molecular Function: protein binding; enzyme binding; nucleic acid binding; RNA binding; nucleotide binding
Biological Process: negative regulation of nuclear mRNA splicing, via spliceosome; RNA splicing; mRNA processing; positive regulation of RNA splicing
Research Articles on U2AF2
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Product Notes
The Mouse U2AF2 u2af2 (Catalog #AAA9339180) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9339180 ELISA Kit recognizes Mouse U2AF2. It is sometimes possible for the material contained within the vial of "U2 small nuclear RNA auxiliary factor 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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