Rat twinfilin, actin-binding protein, homolog 1 (Drosophila) ELISA Kit | TWF1 elisa kit
Rat Twinfilin-1, TWF1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
A6: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. Interacts with G-actin; ADP-actin form and capping protein (CP). May also be able to interact with TWF2 and phosphoinositides, PI(4,5)P2. When bound to PI(4,5)P2, it is down- regulated. Expressed at high levels in the colon, testis, ovary, prostate and lung. Expressed at lower levels in the brain, bladder and heart. Not detected in liver. Belongs to the actin-binding proteins ADF family. Twinfilin subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis
Cellular Component: focal adhesion; myofibril; perinuclear region of cytoplasm; cytoplasm; intercellular junction; actin cytoskeleton; filopodium
Molecular Function: actin monomer binding; phosphatidylinositol-4,5-bisphosphate binding; protein-tyrosine kinase activity; protein complex binding; ATP binding
Biological Process: peptidyl-tyrosine phosphorylation; sequestering of actin monomers; negative regulation of actin filament polymerization; regulation of actin phosphorylation; barbed-end actin filament capping
Research Articles on TWF1
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Product Notes
The Rat TWF1 twf1 (Catalog #AAA9328428) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9328428 ELISA Kit recognizes Rat TWF1. It is sometimes possible for the material contained within the vial of "twinfilin, actin-binding protein, homolog 1 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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