Human Transcription termination factor 2 ELISA Kit | TTF2 elisa kit
Human Transcription termination factor 2 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing. [provided by RefSeq, Jul 2008]
Uniprot Description
TTF2: DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May contribute to mitotic transcription repression. May also be involved in pre-mRNA splicing. Belongs to the SNF2/RAD54 helicase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Helicase; EC 3.6.1.-; Transcription regulation; EC 3.6.4.-; DNA-binding; RNA splicing
Chromosomal Location of Human Ortholog: 1p22
Cellular Component: cytoplasm; spliceosome; transcription elongation factor complex
Molecular Function: ATP binding; ATP-dependent helicase activity; DNA binding; DNA-dependent ATPase activity; protein binding; zinc ion binding
Biological Process: mRNA processing; regulation of transcription, DNA-dependent; RNA splicing; termination of RNA polymerase II transcription; transcription termination
Research Articles on TTF2
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Product Notes
The Human TTF2 ttf2 (Catalog #AAA2881459) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2881459 ELISA Kit recognizes Human TTF2. It is sometimes possible for the material contained within the vial of "Transcription termination factor 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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