SDS-Page
TSHB recombinant protein
TSHB, 21-138aa, Human, His tag, E Coli (Denatured)
Gene Names
TSHB; TSH-B; TSH-BETA
Applications
SDS-Page
Purity
> 85% by SDS-PAGE
Synonyms
TSHB; 21-138aa; Human; His tag; E Coli (Denatured); Thyrotropin subunit beta precursor; Thyroid stimulating hormone; beta; TSH-B; TSH-BETA; TSHB recombinant protein
Host
E Coli
Purity/Purification
> 85% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.5) containing 10% glycerol, 0.4M urea
Concentration
0.25 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MGSFCIPTEY TMHIERRECA YCLTINTTIC AGYCMTRDIN GKLFLPKYAL SQDVCTYRDF IYRTVEIPGC PLHVAPYFSY PVALSCKCGK CNTDYSDCIH EAIKTNYCTK PQKSYLVGFS V
Sequence Length
138
Applicable Applications for TSHB recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for TSHB recombinant protein
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimmers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. TSHB is the beta subunit of thyroid stimulating hormone. Mutations in this gene result in congenital hypothyroidism. Recombinant human TSHB protein, fused to His-tag at N-terminus, was expressed in E Coli
Product Categories/Family for TSHB recombinant protein
References
Hayashizaki Y., Miyai K.. et al. (1985). FEBS Lett. 188:394-400
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
15.9kDa (141aa)
NCBI Official Full Name
thyrotropin subunit beta isoform 1
NCBI Official Synonym Full Names
thyroid stimulating hormone beta
NCBI Official Symbol
TSHB
NCBI Official Synonym Symbols
TSH-B; TSH-BETA
NCBI Protein Information
thyrotropin subunit beta
UniProt Protein Name
Thyrotropin subunit beta
Protein Family
UniProt Gene Name
TSHB
UniProt Synonym Gene Names
TSH-B; TSH-beta
NCBI Description
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
Uniprot Description
Indispensable for the control of thyroid structure and metabolism.
Research Articles on TSHB
Similar Products
Product Notes
The TSHB tshb (Catalog #AAA204965) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's TSHB can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the TSHB tshb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSFCIPTEY TMHIERRECA YCLTINTTIC AGYCMTRDIN GKLFLPKYAL SQDVCTYRDF IYRTVEIPGC PLHVAPYFSY PVALSCKCGK CNTDYSDCIH EAIKTNYCTK PQKSYLVGFS V. It is sometimes possible for the material contained within the vial of "TSHB, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
