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Western Blot (WB)

Mouse anti-Human TSH Monoclonal Antibody | anti-TSHB antibody

Anti-TSH Antibody (26A7D2)

Gene Names
TSHB; TSH-B; TSH-BETA
Reactivity
Human
Applications
ELISA
Purity
Protein A purification
Synonyms
TSH; Monoclonal Antibody; Anti-TSH Antibody (26A7D2); Thyroid-stimulating hormone subunit beta; TSH-B; Thyrotropin beta chain; Thyrotropin subunit beta; anti-TSHB antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG1, kappa
Clone Number
26A7D2
Specificity
Monoclonal antibody to detect TSH. They have no cross-reactivity with human HCG.
Purity/Purification
Protein A purification
Form/Format
Colorless liquid. In PBS buffer, pH7.4, containing 0.02% sodium azide
Concentration
0.5mg/ml (varies by lot)
Applicable Applications for anti-TSHB antibody
ELISA (EIA)
Application Notes
ELISA Capture: 0.5-10ug/ml
ELISA Detection: 0.05-0.2ug/ml
Immunogen
Purified TSH from human pituitary
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use
Shelf life: ~12 months

Western Blot (WB)

Western Blot (WB)
Related Product Information for anti-TSHB antibody
Thyrotropin-stimulating hormone (TSH) is a noncovalently linked glycoprotein heterodimer and is part of a family of pituitary hormones containing a common alpha subunit and a unique beta subunit that confers specificity. Free alpha and beta subunits have essentially no biological activity. TSH (Thyroid stimulating hormone) is secreted from cells in the anterior pituitary and it is indispensable for the control of thyroid structure and metabolism. Free alpha and beta subunits have essentially no biological activity.TSH Antibody is produced from the hybridoma resulting from fusion of Sp2/0 myeloma and lymphocytes obtained from mouse immunized with purified TSH from human pituitary.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,624 Da
NCBI Official Full Name
thyrotropin subunit beta isoform 1
NCBI Official Synonym Full Names
thyroid stimulating hormone, beta
NCBI Official Symbol
TSHB
NCBI Official Synonym Symbols
TSH-B; TSH-BETA
NCBI Protein Information
thyrotropin subunit beta; thyrotropin beta chain
UniProt Protein Name
Thyrotropin subunit beta
Protein Family
UniProt Gene Name
TSHB
UniProt Synonym Gene Names
TSH-B; TSH-beta
UniProt Entry Name
TSHB_HUMAN

NCBI Description

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]

Uniprot Description

TSHB: Indispensable for the control of thyroid structure and metabolism. Belongs to the glycoprotein hormones subunit beta family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p13

Cellular Component: extracellular region

Molecular Function: hormone activity

Biological Process: G-protein coupled receptor protein signaling pathway; anatomical structure morphogenesis; cellular protein metabolic process; cell-cell signaling; response to estrogen stimulus; peptide hormone processing; response to calcium ion; response to vitamin A

Disease: Hypothyroidism, Congenital, Nongoitrous, 4

Research Articles on TSHB

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Product Notes

The TSHB tshb (Catalog #AAA847241) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-TSH Antibody (26A7D2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TSH can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA Capture: 0.5-10ug/ml ELISA Detection: 0.05-0.2ug/ml. Researchers should empirically determine the suitability of the TSHB tshb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TSH, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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