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TSC22 domain family protein 3 (Tsc22d3) Recombinant Protein | Tsc22d3 recombinant protein

Recombinant Rat TSC22 domain family protein 3 (Tsc22d3)

Gene Names
Tsc22d3; Gilz; Dsipi
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
TSC22 domain family protein 3 (Tsc22d3); Recombinant Rat TSC22 domain family protein 3 (Tsc22d3); Tsc22d3 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-134, full length protein
Sequence
MNTEMYQTPMEVAVYQLHNFSISFFSSLLGGDVVSVKLDNSASGASVVALDNKIEQAMDLVKNHLMYAVREEVEVLKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSRLSPEEPAPEAPETPEAPGGSAV
Sequence Length
134
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Tsc22d3 recombinant protein
This protein shares significant sequence identity with the murine TSC-22 and Drosophila shs, both of which are leucine zipper proteins, that function as transcriptional regulators. The expression of this gene is stimulated by glucocorticoids and interleukin 10, and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid and chemokine. Transcript variants encoding different isoforms have been identified for this gene.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14,836 Da
NCBI Official Full Name
TSC22 domain family protein 3
NCBI Official Synonym Full Names
TSC22 domain family, member 3
NCBI Official Symbol
Tsc22d3
NCBI Official Synonym Symbols
Gilz; Dsipi
NCBI Protein Information
TSC22 domain family protein 3
UniProt Protein Name
TSC22 domain family protein 3
UniProt Gene Name
Tsc22d3
UniProt Synonym Gene Names
Dsipi; Gilz

NCBI Description

may play a role in urinary Na(+) and K(+) excretion [RGD, Feb 2006]

Uniprot Description

Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG ().

Research Articles on Tsc22d3

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Product Notes

The Tsc22d3 tsc22d3 (Catalog #AAA1485287) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-134, full length protein. The amino acid sequence is listed below: MNTEMYQTPM EVAVYQLHNF SISFFSSLLG GDVVSVKLDN SASGASVVAL DNKIEQAMDL VKNHLMYAVR EEVEVLKEQI RELVEKNSQL ERENTLLKTL ASPEQLEKFQ SRLSPEEPAP EAPETPEAPG GSAV. It is sometimes possible for the material contained within the vial of "TSC22 domain family protein 3 (Tsc22d3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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