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Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded mouse lung using TSC22D3 Polyclonal Antibody at dilution of 1:300.)
Rabbit anti-Mouse, Rat TSC22D3 Polyclonal Antibody | anti-TSC22D3 antibody
TSC22D3 Polyclonal Antibody
Gene Names
Tsc22d3; DIP; Gilz; Dsip1; Tilz3; TSC-22R
Reactivity
Mouse, Rat
Applications
Immunohistochemistry
Purity
Affinity purification
Synonyms
TSC22D3; Polyclonal Antibody; TSC22D3 Polyclonal Antibody; Delta sleep-inducing peptide immunoreactor; DIP; DSIP immunoreactive leucine zipper protein; DSIP-immunoreactive peptide; Dsip1; Dsipi; GILZ; Glucocorticoid-induced leucine zipper protein; hDIP; Protein DIP; T22D3; TSC-22-like protein; TSC-22-related protein; TSC-22R; TSC22 domain family protein 3; TSC22 domain family; member 3; TSC22 related inducible leucine zipper 3; anti-TSC22D3 antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4.
Sequence Length
80
Applicable Applications for anti-TSC22D3 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:300-1:800
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse GILZ.
Note
Centrifuge before opening to ensure complete recovery of vial contents.
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded mouse lung using TSC22D3 Polyclonal Antibody at dilution of 1:300.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded mouse lung using TSC22D3 Polyclonal Antibody at dilution of 1:300.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded mouse spleen using TSC22D3 Polyclonal Antibody at dilution of 1:300.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded mouse spleen using TSC22D3 Polyclonal Antibody at dilution of 1:300.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded rat brain using TSC22D3 Polyclonal Antibody at dilution of 1:300.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded rat brain using TSC22D3 Polyclonal Antibody at dilution of 1:300.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded rat testis using TSC22D3 Polyclonal Antibody at dilution of 1:300.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded rat testis using TSC22D3 Polyclonal Antibody at dilution of 1:300.)
Related Product Information for anti-TSC22D3 antibody
The protein encoded by this gene shares significant sequence identity with the murine TSC-22 and Drosophila shs, both of which are leucine zipper proteins, that function as transcriptional regulators. The expression of this gene is stimulated by glucocorticoids and interleukin 10, and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid and chemokine. Transcript variants encoding different isoforms have been identified for this gene.
Product Categories/Family for anti-TSC22D3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
TSC22 domain family protein 3 isoform 1
NCBI Official Synonym Full Names
TSC22 domain family, member 3
NCBI Official Symbol
Tsc22d3
NCBI Official Synonym Symbols
DIP; Gilz; Dsip1; Tilz3; TSC-22R
NCBI Protein Information
TSC22 domain family protein 3
UniProt Protein Name
TSC22 domain family protein 3
Protein Family
UniProt Gene Name
Tsc22d3
UniProt Synonym Gene Names
Dsip1; Dsipi; Gilz; Tilz3
Uniprot Description
Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities (). Isoform 1 and isoform 4 inhibit myogenic differentiation and mediate anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG.
Research Articles on TSC22D3
Similar Products
Product Notes
The TSC22D3 tsc22d3 (Catalog #AAA2556185) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TSC22D3 Polyclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TSC22D3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:300-1:800. Researchers should empirically determine the suitability of the TSC22D3 tsc22d3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TSC22D3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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