Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Western blot analysis of TMEM88 in human brain tissue lysate with TMEM88 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)

TYW2 Blocking Peptide | TRMT12 blocking peptide

TYW2 Peptide

Gene Names
TRMT12; TYW2; TRM12
Applications
Blocking (BL)
Synonyms
TYW2; TYW2 Peptide; TRM12; tRNA wybutosine-synthesizing protein 2 homolog; Alpha-amino-alpha-carboxypropyl transferase TYW2; tRNA-yW-synthesizing protein 2; tRNA methyltransferase 12 homolog; TRMT12 blocking peptide
Ordering
For Research Use Only!
Form/Format
Liquid
Concentration
200 ug/mL (varies by lot)
Sequence Length
448
Applicable Applications for TRMT12 blocking peptide
Blocking (BL)
Application Notes
TYW2 peptide is used for blocking the activity of TYW2 antibody.
Species
Human
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location
19 amino acids near the amino terminus of human TYW2.
Preparation and Storage
Store TYW2 peptide at -20 degree C, stable for one year.

Western Blot (WB)

(Western blot analysis of TMEM88 in human brain tissue lysate with TMEM88 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)

Western Blot (WB) (Western blot analysis of TMEM88 in human brain tissue lysate with TMEM88 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50,236 Da
NCBI Official Full Name
tRNA wybutosine-synthesizing protein 2 homolog
NCBI Official Synonym Full Names
tRNA methyltransferase 12 homolog (S. cerevisiae)
NCBI Official Symbol
TRMT12
NCBI Official Synonym Symbols
TYW2; TRM12
NCBI Protein Information
tRNA wybutosine-synthesizing protein 2 homolog; tRNA-yW synthesizing protein 2; tRNA-yW-synthesizing protein 2; tRNA methyltranferase 12 homolog; homolog of yeast tRNA methyltransferase; alpha-amino-alpha-carboxypropyl transferase TYW2; tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase
UniProt Protein Name
tRNA wybutosine-synthesizing protein 2 homolog
UniProt Gene Name
TRMT12
UniProt Synonym Gene Names
TRM12; TYW2; tRNA-yW-synthesizing protein 2
UniProt Entry Name
TYW2_HUMAN

NCBI Description

Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008]

Uniprot Description

TRMT12: Probable S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Belongs to the TRM5 / TYW2 family.

Protein type: EC 2.5.1.114; Methyltransferase

Chromosomal Location of Human Ortholog: 8q24.13

Molecular Function: transferase activity

Biological Process: tRNA processing

Research Articles on TRMT12

Similar Products

Product Notes

The TRMT12 trmt12 (Catalog #AAA152812) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TYW2 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). TYW2 peptide is used for blocking the activity of TYW2 antibody. Researchers should empirically determine the suitability of the TRMT12 trmt12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TYW2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.