Human translocation associated membrane protein 2 ELISA Kit | TRAM2 elisa kit

Human TransloCating chain-associated membrane protein 2, TRAM2 ELISA Kit

Cat. Num. AAA9328992

• Reactivity: Human
• Synonyms: translocation associated membrane protein 2; Human TransloCating chain-associated membrane protein 2; TRAM2 ELISA Kit; Human Translocating chain-associated membrane protein 2 (TRAM2) ELISA kit; KIAA0057; TRAM-like protein; translocation-associated membrane protein 2; TRAM2 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Mouse Body Fluids, Tissue Homogenates, Secretions Or Feces Samples
• Assay Type: Quantitative Sandwich
• Detection Range: 0.25 ng/ml-8 ng/ml
• Sensitivity: 0.1 ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for TRAM2 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of TRAF6 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 6912450
• NCBI GeneID: 9697
• NCBI Accession #: NP_036420.1
• NCBI GenBank Nucleotide #: NM_012288.3
• UniProt Accession #: Q15035; A8K6T6
• Molecular Weight: 43,328 Da
• NCBI Official Full Name: translocating chain-associated membrane protein 2
• NCBI Official Synonym Full Names: translocation associated membrane protein 2
• NCBI Official Symbol: TRAM2
• NCBI Protein Information: translocating chain-associated membrane protein 2; TRAM-like protein
• UniProt Protein Name: Translocating chain-associated membrane protein 2
• Protein Family: Translocating chain-associated membrane protein
• UniProt Gene Name: TRAM2
• UniProt Synonym Gene Names: KIAA0057
• UniProt Entry Name: TRAM2_HUMAN

NCBI Description

TRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum (ER) membrane.[supplied by OMIM, Jul 2004]

Uniprot Description

TRAM2: Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Belongs to the TRAM family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6p21.1-p12

Cellular Component: integral to membrane

Molecular Function: protein binding

Biological Process: protein transport; collagen biosynthetic process