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Tumor Protein P53 Regulated Apoptosis Inducing Protein 1 Recombinant Protein | TP53AIP1  recombinant protein

Recombinant Human Tumor Protein P53 Regulated Apoptosis Inducing Protein 1

Gene Names
TP53AIP1; P53AIP1
Purity
Greater than 85.0% as determined by SDS-PAGE.
Synonyms
Tumor Protein P53 Regulated Apoptosis Inducing Protein 1; Recombinant Human Tumor Protein P53 Regulated Apoptosis Inducing Protein 1; TP53AIP1 Human; Tumor Protein P53 Regulated Apoptosis Inducing Protein 1 Human Recombinant; 800x600 p53-regulated apoptosis-inducing protein 1; TP53AIP1; p53AIP1; P53-regulated apoptosis-inducing protein 1 isoform a; TPIP1; P53AIP1. 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Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Form/Format
The TP53AIP1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHHSSGLVPRGSHMGSSSEASFR SAQASCSGAR RQGLGRGDQN LSVMPPNGRA QTHTPGWVSD PLVLGAQVHG GCRGIEALSV SSGSWSSATVWILTGLGLGL SRPFLPGATV LRDRPLGSAF ELSYDQKKAP LRLQ
Sequence Length
120
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Related Product Information for TP53AIP1  recombinant protein
Description: TP53AIP1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 144 amino acids (1-124) and having a molecular mass of 15kDa.TP53AIP1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: Tumor Protein P53 Regulated Apoptosis Inducing Protein 1 (TP53AIP1) is expressed mainly in the thymus, and is localized to the mitochondrion. p53 induces TP53AIP1 production which then mediates p53- dependent apoptosis. Alternatively spliced transcript variants encoding diverse isoforms are known for TP53AIP1.
Product Categories/Family for TP53AIP1  recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
12,594 Da
NCBI Official Full Name
p53-regulated apoptosis-inducing protein 1 isoform c
NCBI Official Synonym Full Names
tumor protein p53 regulated apoptosis inducing protein 1
NCBI Official Symbol
TP53AIP1
NCBI Official Synonym Symbols
P53AIP1
NCBI Protein Information
p53-regulated apoptosis-inducing protein 1
UniProt Protein Name
p53-regulated apoptosis-inducing protein 1
UniProt Gene Name
TP53AIP1
UniProt Synonym Gene Names
p53AIP1
UniProt Entry Name
TPIP1_HUMAN

NCBI Description

This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Uniprot Description

p53AIP1: May play an important role in mediating p53/TP53- dependent apoptosis. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Mitochondrial

Chromosomal Location of Human Ortholog: 11q24

Cellular Component: mitochondrion

Biological Process: apoptosis

Research Articles on TP53AIP1 

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Product Notes

The TP53AIP1  tp53aip1 (Catalog #AAA146320) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSSSE ASFR SAQASCSGAR RQGLGRGDQN LSVMPPNGRA QTHTPGWVSD PLVLGAQVHG GCRGIEALSV SSGSWSSATV WILTGLGLGL SRPFLPGATV LRDRPLGSAF ELSYDQKKAP LRLQ. It is sometimes possible for the material contained within the vial of "Tumor Protein P53 Regulated Apoptosis Inducing Protein 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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