Torsin-1A (TOR1A) Recombinant Protein | TOR1A recombinant protein
Recombinant Cricetus cricetus Torsin-1A (TOR1A)
NCBI and Uniprot Product Information
Uniprot Description
Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates. Involved in the regulation of synaptic vesicle recycling, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN). In the nucleus, may link the cytoskeleton with the nuclear envelope, this mechanism seems to be crucial for the control of nuclear polarity, cell movement and, specifically in neurons, nuclear envelope integrity. Participates in the cellular trafficking and may regulate the subcellular location of multipass membrane proteins such as the dopamine transporter SLC6A3, leading to the modulation of dopamine neurotransmission. In the endoplasmic reticulum, plays a role in the quality control of protein folding by increasing clearance of misfolded proteins such as SGCE variants or holding them in an intermediate state for proper refolding. May have a redundant function with TOR1B in non-neural tissues ().
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Product Notes
The TOR1A tor1a (Catalog #AAA1398681) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-273, Full length protein. The amino acid sequence is listed below: AECCGQKRSL SREALQKDLD DKLFGQHLAK KVILNAVSGF LSNPKPKKPL TLSLHGWTGT GKNFASKIIA ENIYEGGLNS DYVHLFVATL HFPHASNVTL YKDQLQMWIR GNVSACARSI FIFDEMDKMH AGLIDAIKPF LDYYDVVDEV SYQKAIFIFL SNAGAERITD VALDFWKSGK QREEIKLRDM EHALAVSVFN NKNSGFWHSS LIDRNLIDYF VPFLPLEYKH LKMCIRVEMQ SRGYEVDEDI ISKVAEEMTF FPKEERVFSD KGC. It is sometimes possible for the material contained within the vial of "Torsin-1A (TOR1A), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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